Stem-loop sequence hsa-mir-518c

Accession

MI0003159 (change log)

Symbol

HGNC:MIR518C

Description

Homo sapiens miR-518c stem-loop

Gene family

MIPF0000020; mir-515

Literature search

16 open access papers mention hsa-mir-518c
(20 sentences)

Stem-loop

   gcgagaaga     u        u              a   uc    g  u 
5'          ucuca gcugugac cucuggagggaagc cuu  uguu uc g
            ||||| |||||||| |||||||||||||| |||  |||| || a
3'          agagu uggcauug gagauuucucuucg gaa  acaa ag a
   ----cgaaa     u        u              c   --    a  a 

Deep sequencing

287 reads, 5.8 reads per million, 69 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53708735-53708835 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000464185 ; CTD-2245F17.3-001; intron 4

  ENST00000597550 ; CTD-2245F17.3-001; intron 4

Clustered miRNAs

< 10kb from hsa-mir-518c

• hsa-mir-518f: chr19: 53700015-53700101 [+]
• hsa-mir-520b: chr19: 53701227-53701287 [+]
• hsa-mir-518b: chr19: 53702737-53702819 [+]
• hsa-mir-526a-1: chr19: 53706252-53706336 [+]
• hsa-mir-520c: chr19: 53707453-53707539 [+]
• hsa-mir-518c: chr19: 53708735-53708835 [+]
• hsa-mir-524: chr19: 53711002-53711088 [+]
• hsa-mir-517a: chr19: 53712268-53712354 [+]
• hsa-mir-519d: chr19: 53713347-53713434 [+]
• hsa-mir-521-2: chr19: 53716594-53716680 [+]

Database links

• EntrezGene:MIR518C
• HGNC:MIR518C
• miRBase Tracker:MI0003159

Mature sequence hsa-miR-518c-5p

• Accession: MIMAT0002847
• Previous IDs: hsa-miR-518c*
• Sequence: 24 - ucucuggagggaagcacuuucug - 46
• Deep sequencing: 68 reads, 36 experiments
• Evidence: experimental; array-cloned [1]
• Predicted targets:
  • TargetMiner:hsa-miR-518c-5p
  • TargetScanVert:hsa-miR-518c-5p
  • miRDB:hsa-miR-518c-5p
  • microrna.org:hsa-miR-518c-5p

Mature sequence hsa-miR-518c-3p

• Accession: MIMAT0002848
• Previous IDs: hsa-miR-518c
• Sequence: 62 - caaagcgcuucucuuuagagugu - 84
• Deep sequencing: 87 reads, 37 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • TargetMiner:hsa-miR-518c-3p
  • TargetScanVert:hsa-miR-518c-3p
  • miRDB:hsa-miR-518c-3p
  • microrna.org:hsa-miR-518c-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).