Stem-loop sequence hsa-mir-523

Accession

MI0003153 (change log)

Symbol

HGNC:MIR523

Description

Homo sapiens miR-523 stem-loop

Gene family

MIPF0000020; mir-515

Literature search

4 open access papers mention hsa-mir-523
(10 sentences)

Stem-loop

        ugcu           g          u    guug  u 
5' ucuca    gugacccucua agggaagcgc uucu    uc g
   |||||    ||||||||||| |||||||||| ||||    || a
3' agagu    cauugggagau ucccuucgcg aaga    ag a
        uucc           a          c    --aa  a 

Deep sequencing

568 reads, 3.28 reads per million, 61 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53698385-53698471 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-523

• hsa-mir-1283-1: chr19: 53688481-53688567 [+]
• hsa-mir-520a: chr19: 53690881-53690965 [+]
• hsa-mir-526b: chr19: 53694393-53694475 [+]
• hsa-mir-519b: chr19: 53695213-53695293 [+]
• hsa-mir-525: chr19: 53697533-53697617 [+]
• hsa-mir-523: chr19: 53698385-53698471 [+]
• hsa-mir-518f: chr19: 53700015-53700101 [+]
• hsa-mir-520b: chr19: 53701227-53701287 [+]
• hsa-mir-518b: chr19: 53702737-53702819 [+]
• hsa-mir-526a-1: chr19: 53706252-53706336 [+]
• hsa-mir-520c: chr19: 53707453-53707539 [+]

Database links

• EntrezGene:MIR523
• HGNC:MIR523
• RNAcentral:URS000068F03F_9606
• miRBase Tracker:MI0003153

Mature sequence hsa-miR-523-5p

• Accession: MIMAT0005449
• Previous IDs: hsa-miR-523*
• Sequence: 16 - cucuagagggaagcgcuuucug - 37
• Deep sequencing: 509 reads, 49 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS00005ECFE5_9606
• Predicted targets:
  • TargetMiner:hsa-miR-523-5p
  • TargetScanVert:hsa-miR-523-5p
  • miRDB:hsa-miR-523-5p
  • microrna.org:hsa-miR-523-5p

Mature sequence hsa-miR-523-3p

• Accession: MIMAT0002840
• Previous IDs: hsa-miR-523
• Sequence: 53 - gaacgcgcuucccuauagagggu - 75
• Deep sequencing: 55 reads, 21 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • TargetMiner:hsa-miR-523-3p
  • TargetScanVert:hsa-miR-523-3p
  • miRDB:hsa-miR-523-3p
  • microrna.org:hsa-miR-523-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).