Stem-loop sequence hsa-mir-409

Accession

MI0001735 (change log)

Symbol

HGNC:MIR409

Description

Homo sapiens miR-409 stem-loop

Gene family

MIPF0000018; mir-154

Literature search

56 open access papers mention hsa-mir-409
(185 sentences)

Stem-loop

   u     u  gg   a    ac         -    - auc 
5'  gguac cg  gag gguu  ccgagcaac uuug c   u
    ||||| ||  ||| ||||  ||||||||| |||| |    
3'  cuaug gc  uuc ccaa  ggcucguug aagc g   g
   a     -  uu   c    gu         u    a cag 

Deep sequencing

19718 reads, 3.91 reads per million, 128 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101065300-101065378 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-409

• hsa-mir-485: chr14: 101055419-101055491 [+]
• hsa-mir-323b: chr14: 101056219-101056300 [+]
• hsa-mir-154: chr14: 101059755-101059838 [+]
• hsa-mir-496: chr14: 101060573-101060674 [+]
• hsa-mir-377: chr14: 101062050-101062118 [+]
• hsa-mir-541: chr14: 101064495-101064578 [+]
• hsa-mir-409: chr14: 101065300-101065378 [+]
• hsa-mir-412: chr14: 101065447-101065537 [+]
• hsa-mir-369: chr14: 101065598-101065667 [+]
• hsa-mir-410: chr14: 101065912-101065991 [+]
• hsa-mir-656: chr14: 101066724-101066801 [+]

Database links

• EntrezGene:MIR409
• HGNC:MIR409
• RNAcentral:URS0000759A5D_9606
• miRBase Tracker:MI0001735

Mature sequence hsa-miR-409-5p

• Accession: MIMAT0001638
• Sequence: 15 - agguuacccgagcaacuuugcau - 37
• Deep sequencing: 5896 reads, 106 experiments
• Evidence: experimental; cloned [1,3-4]
• Database links:
  • RNAcentral:URS0000081E1F_9606
• Predicted targets:
  • TargetMiner:hsa-miR-409-5p
  • TargetScanVert:hsa-miR-409-5p
  • miRDB:hsa-miR-409-5p
  • microrna.org:hsa-miR-409-5p

Mature sequence hsa-miR-409-3p

• Accession: MIMAT0001639
• Sequence: 47 - gaauguugcucggugaaccccu - 68
• Deep sequencing: 13819 reads, 128 experiments
• Evidence: experimental; cloned [1,3-4], array-cloned [2]
• Database links:
  • RNAcentral:URS00002915C8_9606
• Predicted targets:
  • TargetMiner:hsa-miR-409-3p
  • TargetScanVert:hsa-miR-409-3p
  • miRDB:hsa-miR-409-3p
  • microrna.org:hsa-miR-409-3p

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
3. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).