Stem-loop sequence hsa-mir-323b

Accession

MI0014206 (change log)

Symbol

HGNC:MIR323B

Description

Homo sapiens miR-323b stem-loop

Gene family

MIPF0000018; mir-154

Literature search

47 open access papers mention hsa-mir-323b
(109 sentences)

Stem-loop

   u     u             u     gugaguuc         
5'  gguac cggagggagguug ccgug        gcauuauu 
    ||||| ||||||||||||| |||||        ||||||| u
3'  cuaug gcuuuucuccagc ggcac        cguaguaa 
   a     -             u     --auaacc         

Deep sequencing

691 reads, 0 reads per million, 92 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

miR-323b-5p was previously named miR-453 here and in [1,2], but appears to be processed from the same hairpin as miR-332b-3p identified in [3]. Entries for mir-323b and mir-453 are merged here.

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101056219-101056300 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-323b

• hsa-mir-487b: chr14: 101046455-101046538 [+]
• hsa-mir-539: chr14: 101047321-101047398 [+]
• hsa-mir-889: chr14: 101047901-101047979 [+]
• hsa-mir-544a: chr14: 101048658-101048748 [+]
• hsa-mir-655: chr14: 101049550-101049646 [+]
• hsa-mir-487a: chr14: 101052446-101052525 [+]
• hsa-mir-382: chr14: 101054306-101054381 [+]
• hsa-mir-134: chr14: 101054687-101054759 [+]
• hsa-mir-668: chr14: 101055258-101055323 [+]
• hsa-mir-485: chr14: 101055419-101055491 [+]
• hsa-mir-323b: chr14: 101056219-101056300 [+]
• hsa-mir-154: chr14: 101059755-101059838 [+]
• hsa-mir-496: chr14: 101060573-101060674 [+]
• hsa-mir-377: chr14: 101062050-101062118 [+]
• hsa-mir-541: chr14: 101064495-101064578 [+]
• hsa-mir-409: chr14: 101065300-101065378 [+]
• hsa-mir-412: chr14: 101065447-101065537 [+]
• hsa-mir-369: chr14: 101065598-101065667 [+]
• hsa-mir-410: chr14: 101065912-101065991 [+]

Database links

• EntrezGene:MIR323B
• HGNC:MIR323B
• RNAcentral:URS000075B679_9606
• miRBase Tracker:MI0014206

Mature sequence hsa-miR-323b-5p

• Accession: MIMAT0001630
• Previous IDs: hsa-miR-453
• Sequence: 15 - agguuguccguggugaguucgca - 37
• Deep sequencing: 26 reads, 9 experiments
• Evidence: experimental; cloned [1-2]
• Predicted targets:
  • TargetMiner:hsa-miR-323b-5p
  • TargetScanVert:hsa-miR-323b-5p
  • miRDB:hsa-miR-323b-5p
  • microrna.org:hsa-miR-323b-5p

Mature sequence hsa-miR-323b-3p

• Accession: MIMAT0015050
• Sequence: 51 - cccaauacacggucgaccucuu - 72
• Deep sequencing: 665 reads, 91 experiments
• Evidence: experimental; Illumina [3]
• Database links:
  • RNAcentral:URS00003538C1_9606
• Predicted targets:
  • TargetMiner:hsa-miR-323b-3p
  • TargetScanVert:hsa-miR-323b-3p
  • miRDB:hsa-miR-323b-3p
  • microrna.org:hsa-miR-323b-3p

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20300190 "Characterization of the Melanoma miRNAome by Deep Sequencing" Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK PLoS One. 5:e9685(2010).