Stem-loop sequence hsa-mir-423

AccessionMI0001445 (change log)
Symbol HGNC:MIR423
DescriptionHomo sapiens miR-423 stem-loop
Gene family MIPF0000329; mir-423
Literature search

111 open access papers mention hsa-mir-423
(442 sentences)

   -----auaa       u            -ag   g    a     cua 
5'          aggaagu aggcugaggggc   aga cgag cuuuu   u
            ||||||| ||||||||||||   ||| |||| |||||   u
3'          uccuucg ucugacuccccg   ucu gcuc gaaaa   u
   cgcgcccaa       u            gag   g    -     ccu 
Get sequence
Deep sequencing
1696635 reads, 3.71e+03 reads per million, 159 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

miR-423 (renamed miR-423-3p here) is expressed in human promyelocytic leukemia (HL-60) cells [1]. The level of expression was shown to be up-regulated 48 hours after TPA-induction. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr17: 30117079-30117172 [+]
Clustered miRNAs
< 10kb from hsa-mir-423
hsa-mir-423chr17: 30117079-30117172 [+]
hsa-mir-3184chr17: 30117086-30117160 [-]
Database links

Mature sequence hsa-miR-423-5p

Accession MIMAT0004748

17 - 


 - 39

Get sequence
Deep sequencing1299932 reads, 159 experiments
Evidence experimental; cloned [2-4], Northern [4], Illumina [5]
Database links
Predicted targets

Mature sequence hsa-miR-423-3p

Accession MIMAT0001340
Previous IDshsa-miR-423

53 - 


 - 75

Get sequence
Deep sequencing396664 reads, 157 experiments
Evidence experimental; cloned [1-2], Northern [1]
Database links
Predicted targets


PMID:15325244 "Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells" Kasashima K, Nakamura Y, Kozu T Biochem Biophys Res Commun. 322:403-410(2004).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).
PMID:18230126 "New miRNAs cloned from neuroblastoma" Afanasyeva EA, Hotz-Wagenblatt A, Glatting KH, Westermann F BMC Genomics. 9:52(2008).