Stem-loop sequence rno-mir-21

Accession

MI0000850 (change log)

Description

Rattus norvegicus miR-21 stem-loop

Gene family

MIPF0000060; mir-21

Literature search

236 open access papers mention rno-mir-21
(2443 sentences)

Stem-loop

   u      ccu      gu        a     a     a    u a 
5'  guacca   ugucgg  agcuuauc gacug uguug cugu g a
    ||||||   ||||||  |||||||| ||||| ||||| |||| | u
3'  uauggu   acaguc  ucggguag cugac acaac ggua c c
   c      uuu      ug        -     g     -    - u 

Deep sequencing

8137692 reads, 8.27e+03 reads per million, 510 experiments

Confidence

Annotation confidence: high

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Genome context

• Coordinates (Rnor_6.0; GCA_000001895.4): chr10: 73902210-73902301 [-]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:Mir21
• miRBase Tracker:MI0000850

Mature sequence rno-miR-21-5p

• Accession: MIMAT0000790
• Previous IDs: rno-miR-21
• Sequence: 18 - uagcuuaucagacugauguuga - 39
• Deep sequencing: 8052247 reads, 510 experiments
• Evidence: experimental; cloned [1-4], SOLiD [5]
• Predicted targets:
  • TargetScanVert:rno-miR-21-5p
  • miRDB:rno-miR-21-5p
  • microrna.org:rno-miR-21-5p

Mature sequence rno-miR-21-3p

• Accession: MIMAT0004711
• Previous IDs: rno-miR-21*
• Sequence: 56 - caacagcagucgaugggcuguc - 77
• Deep sequencing: 81822 reads, 498 experiments
• Evidence: experimental; cloned [3], SOLiD [5]
• Predicted targets:
  • TargetScanVert:rno-miR-21-3p
  • miRDB:rno-miR-21-3p
  • microrna.org:rno-miR-21-3p

References

1. PMID:14691248 "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons" Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G Proc Natl Acad Sci U S A. 101:360-365(2004).
2. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:17805466 "Cloning and identification of novel microRNAs from rat hippocampus" He X, Zhang Q, Liu Y, Pan X Acta Biochim Biophys Sin (Shanghai). 39:708-714(2007).
5. PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).