Stem-loop sequence hsa-mir-345

AccessionMI0000825 (change log)
Symbol HGNC:MIR345
DescriptionHomo sapiens miR-345 stem-loop
Gene family MIPF0000189; mir-345
Literature search

39 open access papers mention hsa-mir-345
(133 sentences)

   ---------acc       u      g u       a  c         ug u 
5'             caaaccc aggucu c gacuccu gu cagggcucg  a g
               ||||||| |||||| | ||||||| || |||||||||  |  
3'             guuuggg uccgga g cugggga ca gucccgggu  u g
   cgacagcuauaa       -      g u       g  a         gg c 
Get sequence
Deep sequencing
49391 reads, 123 reads per million, 155 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

This sequence is the predicted human homologue [2] of a sequence cloned from rat neuronal tissue [1], later validated in human [3,4]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr14: 100307859-100307956 [+]
OTTHUMT00000413938 ; EML1-004; intron 1
OTTHUMT00000413939 ; EML1-006; intron 1
OTTHUMT00000413940 ; EML1-003; intron 1
OTTHUMT00000413941 ; EML1-007; intron 1
OTTHUMT00000413942 ; EML1-008; intron 1
OTTHUMT00000413943 ; EML1-001; intron 1
OTTHUMT00000413944 ; EML1-002; intron 1
OTTHUMT00000413945 ; EML1-009; intron 1
OTTHUMT00000413946 ; EML1-010; intron 1
OTTHUMT00000413947 ; EML1-011; intron 1
OTTHUMT00000413948 ; EML1-012; intron 1
ENST00000554479 ; EML1-004; intron 1
ENST00000555145 ; EML1-006; intron 1
ENST00000327921 ; EML1-003; intron 1
ENST00000556199 ; EML1-007; intron 1
ENST00000556835 ; EML1-008; intron 1
ENST00000262233 ; EML1-001; intron 1
ENST00000334192 ; EML1-002; intron 1
ENST00000555096 ; EML1-009; intron 1
ENST00000556714 ; EML1-010; intron 1
ENST00000553720 ; EML1-011; intron 1
ENST00000556947 ; EML1-012; intron 1
Database links

Mature sequence hsa-miR-345-5p

Accession MIMAT0000772
Previous IDshsa-miR-345

18 - 


 - 39

Get sequence
Deep sequencing48748 reads, 154 experiments
Evidence experimental; cloned [3-4], Northern [3]
Database links
Predicted targets

Mature sequence hsa-miR-345-3p

Accession MIMAT0022698

54 - 


 - 75

Get sequence
Deep sequencing448 reads, 70 experiments
Evidence not experimental
Database links
Predicted targets


PMID:14691248 "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons" Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G Proc Natl Acad Sci U S A. 101:360-365(2004).
PMID:15978578 "Identification of human fetal liver miRNAs by a novel method" Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X FEBS Lett. 579:3849-3854(2005).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).