Stem-loop sequence mmu-mir-181b-1

Accession

MI0000723 (change log)

Previous IDs

mmu-mir-181b

Symbol

MGI:Mir181b-1

Description

Mus musculus miR-181b-1 stem-loop

Gene family

MIPF0000007; mir-181

Literature search

165 open access papers mention mmu-mir-181b-1
(1244 sentences)

Stem-loop

   a       aucaa         cug          gaa  g 
5'  ggucaca     cauucauug   ucgguggguu   cu u
    |||||||     |||||||||   ||||||||||   ||  
3'  ccggugu     guaaguaac   agucacucga   ga g
   -       -caac         --a          aaa  u 

Deep sequencing

1502039 reads, 2.43e+03 reads per million, 107 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr1: 137966639-137966718 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000113293 ; RP23-44N5.6-001; exon 1

  OTTMUST00000113282 ; RP23-393I12.2-001; intron 2

  ENSMUST00000182158 ; A430106G13Rik-001; exon 1

  ENSMUST00000182127 ; Gm4258-001; intron 2

  antisense

  OTTMUST00000113287 ; RP23-44N5.2-001; intron 1

  OTTMUST00000113288 ; RP23-44N5.2-002; intron 1

  ENSMUST00000182424 ; Gm26936-001; intron 1

  ENSMUST00000182680 ; Gm26936-002; intron 1

Clustered miRNAs

< 10kb from mmu-mir-181b-1

• mmu-mir-181a-1: chr1: 137966455-137966541 [+]
• mmu-mir-181b-1: chr1: 137966639-137966718 [+]

Database links

• EntrezGene:Mir181b-1
• MGI:Mir181b-1
• RNAcentral:URS000075CE6A_10090
• miRBase Tracker:MI0000723

Mature sequence mmu-miR-181b-5p

• Accession: MIMAT0000673
• Previous IDs: mmu-miR-181b
• Sequence: 12 - aacauucauugcugucgguggguu - 35
• Deep sequencing: 3015553 reads, 107 experiments
• Evidence: experimental; cloned [2-4], Illumina [5-6]
• Database links:
  • RNAcentral:URS0000605E00_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-181b-5p
  • miRDB:mmu-miR-181b-5p
  • microrna.org:mmu-miR-181b-5p

Mature sequence mmu-miR-181b-1-3p

• Accession: MIMAT0017067
• Previous IDs: mmu-miR-181b-1*
• Sequence: 52 - cucacugaacaaugaaugcaa - 72
• Deep sequencing: 7114 reads, 91 experiments
• Evidence: experimental; 454 [6], Illumina [7]
• Database links:
  • RNAcentral:URS00003526F0_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-181b-1-3p
  • miRDB:mmu-miR-181b-1-3p

References

1. PMID:12624257 "Vertebrate microRNA genes" Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP Science. 299:1540(2003).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
7. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).