miRBase entry: rno-mir-503-2

Stem-loop rno-mir-503-2


Accession
MI0031773
Description
Rattus norvegicus rno-mir-503-2 precursor miRNA
Gene family
MIPF0000183; mir-503

Literature search
22 open access papers mention rno-mir-503-2
(204 sentences)

Sequence

12639 reads, 35 reads per million, 424 experiments
ugcccUAGCAGCGGGAACAGUACUGCAGugaguguuuggugcccuGGAGUAUUGUUUCCGCUGCCUGGgua
(((((..(((((((((((((((((.(((.(.((.......)))))).)))))))))))))))))..)))))

Structure
     UA                 G   u a  gu 
ugccc  GCAGCGGGAACAGUACU CAG g gu  u
|||||  ||||||||||||||||| ||| | ||  u
augGG  CGUCGCCUUUGUUAUGA Guc c cg  g
     UC                 G   - -  ug 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chrX: 158584857-158584927 [+]
Clustered miRNAs
4 other miRNAs are < 10 kb from rno-mir-503-2
Name Accession Chromosome Start End Strand Confidence




Database links

Mature rno-miR-503-5p

Accession MIMAT0003213
Description Rattus norvegicus rno-miR-503-5p mature miRNA
Sequence 6 - UAGCAGCGGGAACAGUACUGCAG - 28
Evidence experimental
cloned [1-2], SOLiD [3]

Mature rno-miR-503-3p

Accession MIMAT0017224
Description Rattus norvegicus rno-miR-503-3p mature miRNA
Sequence 46 - GGAGUAUUGUUUCCGCUGCCUGG - 68
Evidence experimental
SOLiD [3]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  3. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267