Stem-loop cin-let-7b

Accession

MI0007151

Description

Ciona intestinalis cin-let-7b precursor miRNA

Gene family

MIPF0000002; let-7

Literature search

3 open access papers mention cin-let-7b
(18 sentences)

Sequence

10058 reads, 3522 reads per million, 2 experiments

agguacaccugcuguUGAGGUAGUAGGUUAUGUUGUUgcacauaauacugcauuggagauacACCAUGACCUUCUAACCUCUGCaccaugucuaucacuuucaacaugg
(((....)))..(((.(((((((.((((((((.(((((((........))))........))).)))))))).)).))))).)))((((((..(......)..))))))

Structure

------------agguacaccugc   U     -  U        U   --------    cau 
                        ugu GAGGU AG AGGUUAUG UGU        Ugca   a
                        ||| ||||| || |||||||| |||        ||||    
                        aCG CUCCA UC UCCAGUAC Aca        acgu   a
gguacaacuuucacuaucuguacc   U     A  U        C   uagagguu    cau 

Annotation confidence High

Genome context

4q: 2082788-2082896 [+]

Clustered miRNAs

4 other miRNAs are < 10 kb from cin-let-7b

Mature cin-let-7b-5p

• Accession: MIMAT0006087
• Description: Ciona intestinalis cin-let-7b-5p mature miRNA
• Sequence: 16 - UGAGGUAGUAGGUUAUGUUGUU - 37
• Evidence: experimental ; Illumina [2]

Mature cin-let-7b-3p

• Accession: MIMAT0015249
• Description: Ciona intestinalis cin-let-7b-3p mature miRNA
• Sequence: 63 - ACCAUGACCUUCUAACCUCUGC - 84
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 18339653
   Altered miRNA repertoire in the simplified chordate, Oikopleura dioica
   "Fu X, Adamski M, Thompson EM"
   "Mol Biol Evol (2008) 25:1067-1080


2. PubMed ID: 20370911
   miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data
   Hendrix D, Levine M, Shi W
   Genome Biol (2010) 11:R39