Stem-loop sequence hsa-mir-873

Accession

MI0005564 (change log)

Symbol

HGNC:MIR873

Description

Homo sapiens miR-873 stem-loop

Gene family

MIPF0000390; mir-873

Literature search

19 open access papers mention hsa-mir-873
(34 sentences)

Stem-loop

   --   u ca   g a      ug g        a  ga 
5'   gug g  uuu c ggaacu  u agucuccu uu  a
     ||| |  ||| | ||||||  | |||||||| ||  a
3'   cac c  aag g ccuuga  a ucagagga aa  a
   aa   c ac   g c      gu g        c  gu 

Deep sequencing

6010 reads, 8.87 reads per million, 124 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr9: 28888879-28888955 [-]
• Overlapping transcripts:

  sense

  ENST00000401120 ; MIR873-201; exon 1

Database links

• EntrezGene:MIR873
• HGNC:MIR873
• RNAcentral:URS0000209F04_9606
• miRBase Tracker:MI0005564

Mature sequence hsa-miR-873-5p

• Accession: MIMAT0004953
• Previous IDs: hsa-miR-873
• Sequence: 11 - gcaggaacuugugagucuccu - 31
• Deep sequencing: 4944 reads, 121 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00004996E9_9606
• Predicted targets:
  • TargetMiner:hsa-miR-873-5p
  • TargetScanVert:hsa-miR-873-5p.1
  • miRDB:hsa-miR-873-5p
  • microrna.org:hsa-miR-873-5p

Mature sequence hsa-miR-873-3p

• Accession: MIMAT0022717
• Sequence: 46 - ggagacugaugaguucccggga - 67
• Deep sequencing: 1065 reads, 55 experiments
• Evidence: not experimental
• Database links:
  • RNAcentral:URS000026C425_9606
• Predicted targets:
  • TargetMiner:hsa-miR-873-3p
  • TargetScanVert:hsa-miR-873-3p
  • miRDB:hsa-miR-873-3p

References

1. PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).