Stem-loop sequence mmu-mir-741

Accession

MI0005205 (change log)

Symbol

MGI:Mir741

Description

Mus musculus miR-741 stem-loop

Literature search

4 open access papers mention mmu-mir-741
(23 sentences)

Stem-loop

   u             u     c  a      aaau 
5'  ugaucuacguaga uggua cu ucaugu    c
    ||||||||||||| ||||| || ||||||    a
3'  auuagauguaucu accgu ga aguacg    u
   a             u     a  g      aaug 

Deep sequencing

168870 reads, 2.33e+03 reads per million, 46 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chrX: 66796805-66796875 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-741

• mmu-mir-881: chrX: 66801944-66802021 [-]
• mmu-mir-878: chrX: 66801508-66801585 [-]
• mmu-mir-880: chrX: 66800530-66800607 [-]
• mmu-mir-463: chrX: 66799223-66799297 [-]
• mmu-mir-741: chrX: 66796805-66796875 [-]
• mmu-mir-471: chrX: 66792595-66792661 [-]
• mmu-mir-883b: chrX: 66789890-66789967 [-]

Database links

• EntrezGene:Mir741
• MGI:Mir741
• RNAcentral:URS000075AEF6_10090
• miRBase Tracker:MI0005205

Mature sequence mmu-miR-741-5p

• Accession: MIMAT0017262
• Previous IDs: mmu-miR-741*
• Sequence: 7 - uacguagauugguaccuaucaug - 29
• Deep sequencing: 1588 reads, 29 experiments
• Evidence: experimental; Illumina [5]
• Database links:
  • RNAcentral:URS00003EDA2A_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-741-5p
  • miRDB:mmu-miR-741-5p

Mature sequence mmu-miR-741-3p

• Accession: MIMAT0004236
• Previous IDs: mmu-miR-741
• Sequence: 45 - ugagagaugccauucuauguaga - 67
• Deep sequencing: 167241 reads, 43 experiments
• Evidence: experimental; cloned [1-2], 454 [3], Illumina [4-5]
• Database links:
  • RNAcentral:URS000015EBFE_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-741-3p
  • miRDB:mmu-miR-741-3p
  • microrna.org:mmu-miR-741-3p

References

1. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17989215 "RNA sequence analysis defines Dicer's role in mouse embryonic stem cells" Calabrese JM, Seila AC, Yeo GW, Sharp PA Proc Natl Acad Sci U S A. 104:18097-18102(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).