miRBase entry: bta-mir-25

Stem-loop bta-mir-25


Accession
MI0005067
Description
Bos taurus bta-mir-25 precursor miRNA
Gene family
MIPF0000013; mir-25

Literature search
20 open access papers mention bta-mir-25
(55 sentences)

Sequence

239343 reads, 2527 reads per million, 76 experiments
ggccaguguugagaggcggagacuugggcaauugcuggacgcugccccgggCAUUGCACUUGUCUCGGUCUGAcagugccggcc
((((.((((((..((((.(((((..(.(((((..((((........))))..))))).)..))))).))))..)))))).))))

Structure
    a      ag    g     uu g     ug    acg 
ggcc guguug  aggc gagac  g gcaau  cugg   c
|||| ||||||  |||| |||||  | |||||  ||||    
ccgg cgugac  UCUG CUCUG  C CGUUA  ggcc   u
    c      AG    G     UU A     Cg    ccg 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature miR-25 sequence identified by Coutinho et al [1] has an additional A base at the 5' end, which conflicts with the draft genome sequence.

Genome context
chr25: 37072717-37072800 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from bta-mir-25
Name Accession Chromosome Start End Strand Confidence




Database links

Mature bta-miR-25

Accession MIMAT0003853
Description Bos taurus bta-miR-25 mature miRNA
Sequence 52 - CAUUGCACUUGUCUCGGUCUGA - 73
Evidence experimental
cloned [1-2], Array [3], qRT-PCR [3]

References

  1. PubMed ID: 17105755
    Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
    "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
    "Physiol Genomics (2007) 29:35-43

  2. PubMed ID: 17306260
    Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
    "Gu Z, Eleswarapu S, Jiang H"
    "FEBS Lett (2007) 581:981-988

  3. PubMed ID: 19170227
    Identification and expression profiling of microRNAs during bovine oocyte maturation using heterologous approach
    "Tesfaye D, Worku D, Rings F, Phatsara C, Tholen E, Schellander K, Hoelker M"
    "Mol Reprod Dev (2009) 76:665-677