miRBase entry: bta-mir-30b

Stem-loop bta-mir-30b


Accession
MI0004761
Description
Bos taurus bta-mir-30b precursor miRNA
Gene family
MIPF0000005; mir-30

Literature search
27 open access papers mention bta-mir-30b
(162 sentences)

Sequence

49265 reads, 888 reads per million, 77 experiments
ccaaguuuucaguucaUGUAAACAUCCUACACUCAGCUguaacacacgagucggCUGGGAGGUGGAUGUUUACUUcagcugacuugga
(((((...((((((...((((((((((.((.((((((((..((......))))))))))..))))))))))))...))))))))))).

Structure
-     uuu      caU          U  -A        ua  ac 
 ccaag   ucaguu   GUAAACAUCC AC  CUCAGCUg  ac  a
 |||||   ||||||   |||||||||| ||  ||||||||  ||   
 gguuc   agucga   CAUUUGUAGG UG  GGGUCggc  ug  c
a     ---      cUU          -  GA        --  ag 


Annotation confidence High
Do you think this miRNA is real?
Comments
High-throughput sequencing suggests that the dominant miRNA arises from the 3' arm of this precursor [2], in contrast to earlier cloning studies.

Genome context
chr14: 8145856-8145943 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from bta-mir-30b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature bta-miR-30b-5p

Accession MIMAT0003547
Description Bos taurus bta-miR-30b-5p mature miRNA
Sequence 17 - UGUAAACAUCCUACACUCAGCU - 38
Evidence experimental
cloned [1-2], Illumina [3]

Mature bta-miR-30b-3p

Accession MIMAT0012534
Description Bos taurus bta-miR-30b-3p mature miRNA
Sequence 55 - CUGGGAGGUGGAUGUUUACUU - 75
Evidence experimental
Illumina [3]

References

  1. PubMed ID: 17105755
    Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
    "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
    "Physiol Genomics (2007) 29:35-43

  2. PubMed ID: 17306260
    Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
    "Gu Z, Eleswarapu S, Jiang H"
    "FEBS Lett (2007) 581:981-988

  3. PubMed ID: 19633723
    Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection
    Glazov EA, Kongsuwan K, Assavalapsakul W, Horwood PF, Mitter N, Mahony TJ
    PLoS One (2009) 4:e6349