Stem-loop sequence mmu-mir-374b

Accession

MI0004125 (change log)

Previous IDs

mmu-mir-374

Symbol

MGI:Mir374b

Description

Mus musculus miR-374b stem-loop

Gene family

MIPF0000288; mir-374

Literature search

18 open access papers mention mmu-mir-374b
(61 sentences)

Stem-loop

   gaa  aau  ---ua      ug au                     u 
5'    ga   cc     cucggg  g  auaauacaaccugcuaagugu c
      ||   ||     ||||||  |  |||||||||||||||||||||  
3'    cu   gg     gagccu  u  uauuauguuggacgauucacg u
   cug  cuc  uauug      gu ac                     a 

Deep sequencing

87280 reads, 233 reads per million, 106 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chrX: 103573060-103573154 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000044290 ; Thcytx-002; intron 9

  OTTMUST00000044291 ; Thcytx-003; intron 10

  OTTMUST00000044293 ; Thcytx-005; intron 10

  OTTMUST00000044239 ; Thcytx-001; intron 10

  ENSMUST00000130063 ; Ftx-002; intron 9

  ENSMUST00000156211 ; Ftx-001; intron 10

  ENSMUST00000145803 ; Ftx-005; intron 10

  ENSMUST00000156240 ; Ftx-003; intron 10

Clustered miRNAs

< 10kb from mmu-mir-374b

• mmu-mir-374c: chrX: 103573085-103573133 [+]
• mmu-mir-374b: chrX: 103573060-103573154 [-]
• mmu-mir-421: chrX: 103572921-103572996 [-]

Database links

• EntrezGene:Mir374
• MGI:Mir374b
• RNAcentral:URS000075A533_10090
• miRBase Tracker:MI0004125

Mature sequence mmu-miR-374b-5p

• Accession: MIMAT0003727
• Previous IDs: mmu-miR-374-5p;mmu-miR-374;mmu-miR-374-5p
• Sequence: 22 - auauaauacaaccugcuaagug - 43
• Deep sequencing: 84137 reads, 106 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS000033F45D_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-374b-5p
  • miRDB:mmu-miR-374b-5p
  • microrna.org:mmu-miR-374b-5p

Mature sequence mmu-miR-374b-3p

• Accession: MIMAT0003728
• Previous IDs: mmu-miR-374-3p;mmu-miR-374*;mmu-miR-374-3p
• Sequence: 59 - gguuguauuaucauuguccgag - 80
• Deep sequencing: 3052 reads, 93 experiments
• Evidence: experimental; MPSS [1], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000441477_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-374b-3p
  • miRDB:mmu-miR-374b-3p
  • microrna.org:mmu-miR-374b-3p

References

1. PMID:16582102 "The expression profile of microRNAs in mouse embryos" Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I Nucleic Acids Res. 34:1765-1771(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).