Stem-loop sequence hsa-mir-1224

Accession

MI0003764 (change log)

Symbol

HGNC:MIR1224

Description

Homo sapiens miR-1224 stem-loop

Gene family

MIPF0000440; mir-1224

Literature search

22 open access papers mention hsa-mir-1224
(194 sentences)

Stem-loop

   g      cuc         a   u  u  cgccggggccgg 
5'  ugagga   gggaggugg ggg gg gc            g
    ||||||   ||||||||| ||| || ||            c
3'  acuccu   uccuccacc ccc cu cg            g
   g      cuc         c   u  u  cucgacuuuguc 

Deep sequencing

17971 reads, 18.3 reads per million, 126 experiments

Confidence

Annotation confidence: low

Feedback: Do you believe this miRNA is real?

Comments

This sequence was identified as a miRNA candidate by Berezikov et al [1], and confirmed later by more extensive cloning [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr3: 184241405-184241489 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000346333 ; EIF2B5-017; intron 15

  ENST00000444495 ; EIF2B5-017; intron 15

Database links

• EntrezGene:MIR1224
• HGNC:MIR1224
• RNAcentral:URS00006378D3_9606
• miRBase Tracker:MI0003764

Mature sequence hsa-miR-1224-5p

• Accession: MIMAT0005458
• Sequence: 1 - gugaggacucgggaggugg - 19
• Deep sequencing: 16141 reads, 81 experiments
• Evidence: experimental; RAKE [1], cloned [2]
• Database links:
  • RNAcentral:URS0000435A77_9606
• Predicted targets:
  • TargetMiner:hsa-miR-1224-5p
  • TargetScanVert:hsa-miR-1224-5p
  • miRDB:hsa-miR-1224-5p
  • microrna.org:hsa-miR-1224-5p

Mature sequence hsa-miR-1224-3p

• Accession: MIMAT0005459
• Sequence: 65 - ccccaccuccucucuccucag - 85
• Deep sequencing: 1776 reads, 69 experiments
• Evidence: experimental; cloned [2]
• Predicted targets:
  • TargetMiner:hsa-miR-1224-3p
  • TargetScanVert:hsa-miR-1224-3p
  • miRDB:hsa-miR-1224-3p
  • microrna.org:hsa-miR-1224-3p

References

1. PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2. PMID:17964270 "Mammalian mirtron genes" Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC Mol Cell. 28:328-336(2007).