Stem-loop hcmv-mir-UL70

Accession

MI0003688

Description

Human cytomegalovirus hcmv-mir-UL70 precursor miRNA

Sequence

gguUGCGUCUCGGCCUCGUCCAGAcuggcgaugagcgccgagagGGGGAUGGGCUGGCGCGCGGcc
((((((((.((((((.(((((...((((((.....)))).))....))))))))))).))))))))

Structure

        C      U     -AGA  -    a 
gguUGCGU UCGGCC CGUCC    cu ggcg u
|||||||| |||||| |||||    || |||| g
ccGGCGCG GGUCGG GUAGG    ga ccgc a
        C      -     GGga  g    g 

Annotation confidence Not enough data

Genome context

HEHCMVCG: 103087-103152 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from hcmv-mir-UL70

Disease association

hcmv-mir-UL70 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hcmv-miR-UL70-5p

• Accession: MIMAT0003342
• Description: Human cytomegalovirus hcmv-miR-UL70-5p mature miRNA
• Sequence: 4 - UGCGUCUCGGCCUCGUCCAGA - 24
• Evidence: experimental ; Northern [1], Illumina [2]

Mature hcmv-miR-UL70-3p

• Accession: MIMAT0003343
• Description: Human cytomegalovirus hcmv-miR-UL70-3p mature miRNA
• Sequence: 45 - GGGGAUGGGCUGGCGCGCGG - 64
• Evidence: experimental ; Northern [1], Illumina [2]

References

1. PubMed ID: 16140786
   Identification and characterization of human cytomegalovirus-encoded microRNAs
   "Grey F, Antoniewicz A, Allen E, Saugstad J, McShea A, Carrington JC, Nelson J"
   "J Virol (2005) 79:12095-12099


2. PubMed ID: 22715351
   The microRNA Transcriptome of Human Cytomegalovirus (HCMV)
   "Meshesha MK, Veksler-Lublinsky I, Isakov O, Reichenstein I, Shomron N, Kedem K, Ziv-Ukelson M, Bentwich Z, Avni YS"
   "Open Virol J (2012) 6:38-48