Stem-loop sequence hsa-mir-660

Accession

MI0003684 (change log)

Symbol

HGNC:MIR660

Description

Homo sapiens miR-660 stem-loop

Gene family

MIPF0000113; mir-188

Literature search

22 open access papers mention hsa-mir-660
(64 sentences)

Stem-loop

   ----------cu    c      -cauac    u      c    u   gaau 
5'             gcuc uucucc      ccau gcauau ggag ugu    u
               |||| ||||||      |||| |||||| |||| |||    c
3'             cgag gggagg      ggua cgugug ccuc aca    u
   gugcuacuguuc    u      acauua    -      u    c   aaac 

Deep sequencing

93741 reads, 510 reads per million, 160 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chrX: 50013241-50013337 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000056562 ; CCNB3-005; intron 1

  OTTHUMT00000056558 ; CCNB3-001; intron 1

  OTTHUMT00000056559 ; CCNB3-002; intron 1

  OTTHUMT00000056560 ; CCNB3-003; intron 1

  OTTHUMT00000056561 ; CCNB3-004; intron 2

  ENST00000491907 ; CCNB3-005; intron 1

  ENST00000376042 ; CCNB3-001; intron 1

  ENST00000376038 ; CCNB3-002; intron 1

  ENST00000476167 ; CCNB3-003; intron 1

  ENST00000493507 ; CCNB3-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-660

• hsa-mir-188: chrX: 50003503-50003588 [+]
• hsa-mir-500a: chrX: 50008431-50008514 [+]
• hsa-mir-362: chrX: 50008964-50009028 [+]
• hsa-mir-501: chrX: 50009722-50009805 [+]
• hsa-mir-500b: chrX: 50010672-50010750 [+]
• hsa-mir-660: chrX: 50013241-50013337 [+]
• hsa-mir-502: chrX: 50014598-50014683 [+]

Database links

• EntrezGene:MIR660
• HGNC:MIR660
• RNAcentral:URS000075D69B_9606
• miRBase Tracker:MI0003684

Mature sequence hsa-miR-660-5p

• Accession: MIMAT0003338
• Previous IDs: hsa-miR-660
• Sequence: 16 - uacccauugcauaucggaguug - 37
• Deep sequencing: 91879 reads, 159 experiments
• Evidence: experimental; Microarray [1], RT-PCR [1], SAGE [1], cloned [2]
• Database links:
  • RNAcentral:URS0000116A70_9606
• Predicted targets:
  • TargetMiner:hsa-miR-660-5p
  • TargetScanVert:hsa-miR-660-5p
  • miRDB:hsa-miR-660-5p
  • microrna.org:hsa-miR-660-5p

Mature sequence hsa-miR-660-3p

• Accession: MIMAT0022711
• Sequence: 52 - accuccugugugcauggauua - 72
• Deep sequencing: 1851 reads, 141 experiments
• Evidence: not experimental
• Database links:
  • RNAcentral:URS00000011DF_9606
• Predicted targets:
  • TargetMiner:hsa-miR-660-3p
  • TargetScanVert:hsa-miR-660-3p
  • miRDB:hsa-miR-660-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).