Stem-loop sequence hsa-mir-33b

Accession

MI0003646 (change log)

Symbol

HGNC:MIR33B

Description

Homo sapiens miR-33b stem-loop

Gene family

MIPF0000070; mir-33

Literature search

121 open access papers mention hsa-mir-33b
(1276 sentences)

Stem-loop

   -----  ---    -   c   c  -          uu         g   g 
5'      gc   gggc ggc ccg gg ugcauugcug  gcauugcac ugu u
        ||   |||| ||| ||| || ||||||||||  ||||||||| ||| g
3'      cg   cccg ccg ggc cc acgugacggc  cgugacgug gcg a
   cacca  guc    g   a   -  g          uc         g   g 

Deep sequencing

11166 reads, 27.3 reads per million, 150 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr17: 17813836-17813931 [-]
• Overlapping transcripts:

  sense

  OTTHUMT00000131929 ; TOM1L2-002; intron 1

  OTTHUMT00000131928 ; TOM1L2-001; intron 1

  OTTHUMT00000443246 ; TOM1L2-010; intron 1

  OTTHUMT00000131931 ; TOM1L2-004; intron 1

  OTTHUMT00000443248 ; TOM1L2-007; intron 1

  OTTHUMT00000443249 ; TOM1L2-009; intron 1

  OTTHUMT00000443250 ; TOM1L2-008; intron 1

  OTTHUMT00000443252 ; TOM1L2-011; intron 1

  OTTHUMT00000443253 ; TOM1L2-012; intron 1

  ENST00000581396 ; TOM1L2-002; intron 1

  ENST00000379504 ; TOM1L2-001; intron 1

  ENST00000318094 ; TOM1L2-010; intron 1

  ENST00000395739 ; TOM1L2-004; intron 1

  ENST00000535933 ; TOM1L2-007; intron 1

  ENST00000540946 ; TOM1L2-009; intron 1

  ENST00000542206 ; TOM1L2-008; intron 1

  ENST00000537091 ; TOM1L2-011; intron 1

  ENST00000579586 ; TOM1L2-012; intron 1

Clustered miRNAs

< 10kb from hsa-mir-33b

• hsa-mir-33b: chr17: 17813836-17813931 [-]
• hsa-mir-6777: chr17: 17813480-17813545 [-]

Database links

• EntrezGene:MIR33B
• HGNC:MIR33B
• RNAcentral:URS000075D54F_9606
• miRBase Tracker:MI0003646

Mature sequence hsa-miR-33b-5p

• Accession: MIMAT0003301
• Previous IDs: hsa-miR-33b
• Sequence: 16 - gugcauugcuguugcauugc - 35
• Deep sequencing: 9770 reads, 142 experiments
• Evidence: experimental; SAGE [1], cloned [2]
• Database links:
  • RNAcentral:URS00004C8DD5_9606
• Predicted targets:
  • TargetMiner:hsa-miR-33b-5p
  • TargetScanVert:hsa-miR-33b-5p
  • miRDB:hsa-miR-33b-5p
  • microrna.org:hsa-miR-33b-5p

Mature sequence hsa-miR-33b-3p

• Accession: MIMAT0004811
• Previous IDs: hsa-miR-33b*
• Sequence: 54 - cagugccucggcagugcagccc - 75
• Deep sequencing: 1236 reads, 88 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00001270D3_9606
• Predicted targets:
  • TargetMiner:hsa-miR-33b-3p
  • TargetScanVert:hsa-miR-33b-3p
  • miRDB:hsa-miR-33b-3p
  • microrna.org:hsa-miR-33b-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).