Stem-loop sequence hsa-mir-589

Accession

MI0003599 (change log)

Symbol

HGNC:MIR589

Description

Homo sapiens miR-589 stem-loop

Gene family

MIPF0000496; mir-589

Literature search

15 open access papers mention hsa-mir-589
(37 sentences)

Stem-loop

   ucca   ugu  cca     cc   a     -a   c  c       u   u 
5'     gcc   gc   gcagc  cug gaacc  cgu ug ucugagc ggg a
       |||   ||   |||||  ||| |||||  ||| || ||||||| ||| c
3'     cgg   cg   cgucg  gac cuugg  gua ac agacuug ucc u
   ---c   --u  -ac     ca   c     cc   a  a       -   g 

Deep sequencing

10580 reads, 8.11 reads per million, 148 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr7: 5495819-5495917 [-]
• Overlapping transcripts:

  sense

  OTTHUMT00000324092 ; FBXL18-002; intron 4

  ENST00000415009 ; FBXL18-002; intron 4

Database links

• EntrezGene:MIR589
• HGNC:MIR589
• RNAcentral:URS000064C5B0_9606
• miRBase Tracker:MI0003599

Mature sequence hsa-miR-589-5p

• Accession: MIMAT0004799
• Previous IDs: hsa-miR-589
• Sequence: 24 - ugagaaccacgucugcucugag - 45
• Deep sequencing: 8383 reads, 143 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00004214BB_9606
• Predicted targets:
  • TargetMiner:hsa-miR-589-5p
  • TargetScanVert:hsa-miR-589-5p
  • miRDB:hsa-miR-589-5p
  • microrna.org:hsa-miR-589-5p

Mature sequence hsa-miR-589-3p

• Accession: MIMAT0003256
• Previous IDs: hsa-miR-589;hsa-miR-589*
• Sequence: 61 - ucagaacaaaugccgguucccaga - 84
• Deep sequencing: 2194 reads, 126 experiments
• Evidence: experimental; SAGE [1]
• Database links:
  • RNAcentral:URS00005F9DAE_9606
• Predicted targets:
  • TargetMiner:hsa-miR-589-3p
  • TargetScanVert:hsa-miR-589-3p
  • miRDB:hsa-miR-589-3p
  • microrna.org:hsa-miR-589-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).