miRBase entry: rno-mir-133b

Stem-loop rno-mir-133b


Accession
MI0003490
Description
Rattus norvegicus rno-mir-133b precursor miRNA
Gene family
MIPF0000029; mir-133

Literature search
85 open access papers mention rno-mir-133b
(341 sentences)

Sequence

461215 reads, 538 reads per million, 413 experiments
cccugcucugGCUGGUCAAACGGAACCAAGUccgucuuccugagaggUUUGGUCCCCUUCAACCAGCUAcagcagggcuggcaa
(((((((.((((((((..((.((.((((((.((.((((...)))))))))))).)).))..)))))))).))))))).......

Structure
-------       c        CA  C  A      U  g    c 
       cccugcu ugGCUGGU  AA GG ACCAAG cc ucuu  
       ||||||| ||||||||  || || |||||| || |||| c
       gggacga AUCGACCA  UU CC UGGUUU gg agag  
aacgguc       c        AC  C  C      -  -    u 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr9: 26795649-26795732 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from rno-mir-133b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature rno-miR-133b-5p

Accession MIMAT0017205
Description Rattus norvegicus rno-miR-133b-5p mature miRNA
Sequence 11 - GCUGGUCAAACGGAACCAAGU - 31
Evidence experimental
SOLiD [3]

Mature rno-miR-133b-3p

Accession MIMAT0003126
Description Rattus norvegicus rno-miR-133b-3p mature miRNA
Sequence 48 - UUUGGUCCCCUUCAACCAGCUA - 69
Evidence experimental
cloned [1-2], SOLiD [3]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  3. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267