miRBase entry: hsa-mir-518f

Stem-loop hsa-mir-518f


Accession
MI0003154
Symbol
HGNC: MIR518F
Description
Homo sapiens hsa-mir-518f precursor miRNA
Gene family
MIPF0000020; mir-515

Literature search
13 open access papers mention hsa-mir-518f
(22 sentences)

Sequence

38 reads, 19 reads per million, 14 experiments
ucucaugcugugaccCUCUAGAGGGAAGCACUUUCUCuugucuaaaagaaaaGAAAGCGCUUCUCUUUAGAGGauuacucuuugaga
(((((....((((.(((((((((((((((.(((((((((......))))...))))).))))))))))))))).))))....)))))

Structure
     ugcu    c               A     ---    gu 
ucuca    guga cCUCUAGAGGGAAGC CUUUC   UCuu  c
|||||    |||| ||||||||||||||| |||||   ||||   
agagu    cauu GGAGAUUUCUCUUCG GAAAG   agaa  u
     uucu    a               C     aaa    aa 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chr19: 53700015-53700101 [+]
Clustered miRNAs
10 other miRNAs are < 10 kb from hsa-mir-518f
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-518f is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-518f-5p

Accession MIMAT0002841
Description Homo sapiens hsa-miR-518f-5p mature miRNA
Sequence 16 - CUCUAGAGGGAAGCACUUUCUC - 37
Evidence experimental
array-cloned [1], cloned [2]

Mature hsa-miR-518f-3p

Accession MIMAT0002842
Description Homo sapiens hsa-miR-518f-3p mature miRNA
Sequence 53 - GAAAGCGCUUCUCUUUAGAGG - 73
Evidence experimental
array-cloned [1], cloned [2]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770