Stem-loop sequence hsa-mir-520a

Accession

MI0003149 (change log)

Symbol

HGNC:MIR520A

Description

Homo sapiens miR-520a stem-loop

Gene family

MIPF0000020; mir-515

Literature search

47 open access papers mention hsa-mir-520a
(152 sentences)

Stem-loop

            u   cc                    g  g    
5' cucaggcug gac  uccagagggaaguacuuucu uu ucu 
   ||||||||| |||  |||||||||||||||||||| || || g
3' gaguuuggc uug  agguuucccuucgugaaaga aa aga 
            u   uc                    a  g    

Deep sequencing

362 reads, 4.76 reads per million, 63 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53690881-53690965 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000464179 ; ZNF665-002; intron 1

  OTTHUMT00000464180 ; ZNF665-001; intron 1

  OTTHUMT00000464181 ; ZNF665-005; intron 1

  OTTHUMT00000464183 ; ZNF665-003; intron 1

  OTTHUMT00000464182 ; ZNF665-004; intron 3

  ENST00000600412 ; ZNF665-002; intron 1

  ENST00000396424 ; ZNF665-001; intron 1

  ENST00000597544 ; ZNF665-005; intron 1

  ENST00000598440 ; ZNF665-003; intron 1

  ENST00000596373 ; ZNF665-004; intron 3

Clustered miRNAs

< 10kb from hsa-mir-520a

• hsa-mir-520f: chr19: 53682159-53682245 [+]
• hsa-mir-515-2: chr19: 53685009-53685091 [+]
• hsa-mir-519c: chr19: 53686469-53686555 [+]
• hsa-mir-1283-1: chr19: 53688481-53688567 [+]
• hsa-mir-520a: chr19: 53690881-53690965 [+]
• hsa-mir-526b: chr19: 53694393-53694475 [+]
• hsa-mir-519b: chr19: 53695213-53695293 [+]
• hsa-mir-525: chr19: 53697533-53697617 [+]
• hsa-mir-523: chr19: 53698385-53698471 [+]
• hsa-mir-518f: chr19: 53700015-53700101 [+]

Database links

• EntrezGene:MIR520A
• HGNC:MIR520A
• miRBase Tracker:MI0003149

Mature sequence hsa-miR-520a-5p

• Accession: MIMAT0002833
• Previous IDs: hsa-miR-520a*
• Sequence: 15 - cuccagagggaaguacuuucu - 35
• Deep sequencing: 95 reads, 36 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • TargetMiner:hsa-miR-520a-5p
  • TargetScanVert:hsa-miR-520a-5p
  • miRDB:hsa-miR-520a-5p
  • microrna.org:hsa-miR-520a-5p

Mature sequence hsa-miR-520a-3p

• Accession: MIMAT0002834
• Previous IDs: hsa-miR-520a
• Sequence: 53 - aaagugcuucccuuuggacugu - 74
• Deep sequencing: 253 reads, 35 experiments
• Evidence: experimental; array-cloned [1]
• Predicted targets:
  • TargetMiner:hsa-miR-520a-3p
  • TargetScanVert:hsa-miR-520a-3p
  • miRDB:hsa-miR-520a-3p
  • microrna.org:hsa-miR-520a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).