Stem-loop sequence hsa-mir-519c

AccessionMI0003148 (change log)
Symbol HGNC:MIR519C
DescriptionHomo sapiens miR-519c stem-loop
Gene family MIPF0000020; mir-515
Literature search

27 open access papers mention hsa-mir-519c
(69 sentences)

         c      c            a         guug  u 
5' ucucag cuguga ccucuagaggga gcgcuuucu    uc g
   |||||| |||||| |||||||||||| |||||||||    || a
3' agaguu gacauu ggagauuuuucu cgugaaaga    ag a
         u      a            a         --aa  a 
Get sequence
Deep sequencing
733 reads, 14.8 reads per million, 88 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

The 5' arm of this precursor expresses a product related to miR-526 (previously named miR-526c here). Landgraf et al. confirm mature miRNA expression from both arms of the precursor [2], leading to the -5p, -3p designations. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr19: 53686469-53686555 [+]
OTTHUMT00000464179 ; ZNF665-002; intron 1
OTTHUMT00000464180 ; ZNF665-001; intron 1
OTTHUMT00000464181 ; ZNF665-005; intron 1
OTTHUMT00000464183 ; ZNF665-003; intron 1
OTTHUMT00000464182 ; ZNF665-004; intron 3
ENST00000600412 ; ZNF665-002; intron 1
ENST00000396424 ; ZNF665-001; intron 1
ENST00000597544 ; ZNF665-005; intron 1
ENST00000598440 ; ZNF665-003; intron 1
ENST00000596373 ; ZNF665-004; intron 3
Clustered miRNAs
< 10kb from hsa-mir-519c
hsa-mir-515-1chr19: 53679003-53679085 [+]
hsa-mir-519echr19: 53679940-53680023 [+]
hsa-mir-520fchr19: 53682159-53682245 [+]
hsa-mir-515-2chr19: 53685009-53685091 [+]
hsa-mir-519cchr19: 53686469-53686555 [+]
hsa-mir-1283-1chr19: 53688481-53688567 [+]
hsa-mir-520achr19: 53690881-53690965 [+]
hsa-mir-526bchr19: 53694393-53694475 [+]
hsa-mir-519bchr19: 53695213-53695293 [+]
Database links

Mature sequence hsa-miR-519c-5p

Accession MIMAT0002831
Previous IDshsa-miR-526c

16 - 


 - 37

Get sequence
Deep sequencing509 reads, 49 experiments
Evidence experimental; array-cloned [1], cloned [2]
Database links
Predicted targets

Mature sequence hsa-miR-519c-3p

Accession MIMAT0002832
Previous IDshsa-miR-519c

54 - 


 - 75

Get sequence
Deep sequencing210 reads, 51 experiments
Evidence experimental; array-cloned [1]
Predicted targets


PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).