Stem-loop sequence hsa-mir-515-1

Accession

MI0003144 (change log)

Symbol

HGNC:MIR515-1

Description

Homo sapiens miR-515-1 stem-loop

Gene family

MIPF0000020; mir-515

Literature search

36 open access papers mention hsa-mir-515-1
(66 sentences)

Stem-loop

        u     c  u           a    uu      gu 
5' ucuca gcagu au cuccaaaagaa gcac  ucuguu  c
   ||||| ||||| || ||||||||||| ||||  ||||||  u
3' agagu uguca ug gagguuuucuu cgug  agacga  g
        u     u  c           c    --      aa 

Deep sequencing

176 reads, 7.27 reads per million, 55 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53679003-53679085 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000464179 ; ZNF665-002; intron 1

  OTTHUMT00000464180 ; ZNF665-001; intron 2

  ENST00000600412 ; ZNF665-002; intron 1

  ENST00000396424 ; ZNF665-001; intron 2

Clustered miRNAs

< 10kb from hsa-mir-515-1

• hsa-mir-512-2: chr19: 53669157-53669254 [+]
• hsa-mir-1323: chr19: 53671968-53672040 [+]
• hsa-mir-498: chr19: 53674197-53674320 [+]
• hsa-mir-520e: chr19: 53675711-53675797 [+]
• hsa-mir-515-1: chr19: 53679003-53679085 [+]
• hsa-mir-519e: chr19: 53679940-53680023 [+]
• hsa-mir-520f: chr19: 53682159-53682245 [+]
• hsa-mir-515-2: chr19: 53685009-53685091 [+]
• hsa-mir-519c: chr19: 53686469-53686555 [+]
• hsa-mir-1283-1: chr19: 53688481-53688567 [+]

Database links

• EntrezGene:MIR515-1
• HGNC:MIR515-1
• RNAcentral:URS00006C1198_9606
• miRBase Tracker:MI0003144

Mature sequence hsa-miR-515-5p

• Accession: MIMAT0002826
• Sequence: 14 - uucuccaaaagaaagcacuuucug - 37
• Deep sequencing: 282 reads, 50 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS00000A68B2_9606
• Predicted targets:
  • TargetMiner:hsa-miR-515-5p
  • TargetScanVert:hsa-miR-515-5p
  • miRDB:hsa-miR-515-5p
  • microrna.org:hsa-miR-515-5p

Mature sequence hsa-miR-515-3p

• Accession: MIMAT0002827
• Sequence: 51 - gagugccuucuuuuggagcguu - 72
• Deep sequencing: 64 reads, 19 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • TargetMiner:hsa-miR-515-3p
  • TargetScanVert:hsa-miR-515-3p
  • miRDB:hsa-miR-515-3p
  • microrna.org:hsa-miR-515-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).