Stem-loop mml-mir-106a

Accession

MI0003107

Description

Macaca mulatta mml-mir-106a precursor miRNA

Gene family

MIPF0000001; mir-17

Literature search

1 open access papers mention mml-mir-106a
(2 sentences)

Sequence

1836 reads, 20 reads per million, 9 experiments

ccuuggccauguAAAAGUGCUUACAGUGCAGGUAGCuuuuugagaucuACUGCAAUGCAAGCACUUCUUACauuaccaugg
((.(((..((((((((((((((.((.(((((.(((.(((...))).)))))))).)).)))))))).))))))..))).))

Structure

  u   cc      -        A  G     G   C   u 
cc ugg  auguAA AAGUGCUU CA UGCAG UAG uuu  
|| |||  |||||| |||||||| || ||||| ||| ||| u
gg acc  uaCAUU UUCACGAA GU ACGUC Auc aga  
  u   au      C        C  A     -   u   g 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chrX: 128132553-128132633 [-]

Clustered miRNAs

5 other miRNAs are < 10 kb from mml-mir-106a

Mature mml-miR-106a-5p

• Accession: MIMAT0002798
• Description: Macaca mulatta mml-miR-106a-5p mature miRNA
• Sequence: 13 - AAAAGUGCUUACAGUGCAGGUAGC - 36
• Evidence: experimental ; Illumina [2]

Mature mml-miR-106a-3p

• Accession: MIMAT0026604
• Description: Macaca mulatta mml-miR-106a-3p mature miRNA
• Sequence: 49 - ACUGCAAUGCAAGCACUUCUUAC - 71
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45