miRBase entry: mml-mir-106b

Stem-loop mml-mir-106b


Accession
MI0003073
Description
Macaca mulatta mml-mir-106b precursor miRNA
Gene family
MIPF0000001; mir-17

Literature search
1 open access papers mention mml-mir-106b
(1 sentences)

Sequence

52859 reads, 421 reads per million, 9 experiments
ccugcuggggcUAAAGUGCUGACAGUGCAGAUagugguccucuccgugcuACCGCACUGUGGGUACUUGCUGcuccagcagg
(((((((((((..(((((((.(((((((.(.((((((......))..))))).))))))).)))))))...)))))))))))

Structure
           -UA       G       A A    --  uc 
ccugcuggggc   AAGUGCU ACAGUGC G Uagu  gg  c
|||||||||||   ||||||| ||||||| | ||||  ||   
ggacgaccucG   UUCAUGG UGUCACG C Aucg  cc  u
           UCG       G       C -    ug  uc 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr3: 125615402-125615483 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from mml-mir-106b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mml-miR-106b-5p

Accession MIMAT0002772
Description Macaca mulatta mml-miR-106b-5p mature miRNA
Sequence 12 - UAAAGUGCUGACAGUGCAGAU - 32
Evidence experimental
Illumina [2]
Database links
Predicted targets

Mature mml-miR-106b-3p

Accession MIMAT0026601
Description Macaca mulatta mml-miR-106b-3p mature miRNA
Sequence 51 - ACCGCACUGUGGGUACUUGCUG - 72
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  2. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45