miRBase entry: mml-mir-20a

Stem-loop mml-mir-20a


Accession
MI0003004
Description
Macaca mulatta mml-mir-20a precursor miRNA
Gene family
MIPF0000001; mir-17

Literature search
2 open access papers mention mml-mir-20a
(4 sentences)

Sequence

46589 reads, 502 reads per million, 9 experiments
guagcacUAAAGUGCUUAUAGUGCAGGUAguguuuaguuaucuACUGCAUUAUGAGCACUUAAAGUacugc
((((.(((.(((((((((((((((((.(((...........))))))))))))))))))))..))).))))

Structure
    c   -A                 G   uguu 
guag acU  AAGUGCUUAUAGUGCAG UAg    u
|||| |||  ||||||||||||||||| |||    a
cguc UGA  UUCACGAGUAUUACGUC Auc    g
    a   AA                 -   uauu 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr17: 73096567-73096637 [+]
Clustered miRNAs
5 other miRNAs are < 10 kb from mml-mir-20a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mml-miR-20a-5p

Accession MIMAT0002704
Description Macaca mulatta mml-miR-20a-5p mature miRNA
Sequence 8 - UAAAGUGCUUAUAGUGCAGGUA - 29
Evidence experimental
Illumina [2]

Mature mml-miR-20a-3p

Accession MIMAT0026597
Description Macaca mulatta mml-miR-20a-3p mature miRNA
Sequence 44 - ACUGCAUUAUGAGCACUUAAAGU - 66
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  2. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45