miRBase entry: mml-mir-103-1

Stem-loop mml-mir-103-1


Accession
MI0002743
Description
Macaca mulatta mml-mir-103-1 precursor miRNA
Gene family
MIPF0000024; mir-103

Literature search
5 open access papers mention mml-mir-103-1
(18 sentences)

Sequence

835966 reads, 5835 reads per million, 9 experiments
uacugcccUCGGCUUCUUUACAGUGCUGCCUUGuugcauauggaucaAGCAGCAUUGUACAGGGCUAUGAaggcauug
...((((.((((((.((.(((((((((((.(((.(.(....).).)))))))))))))).))))))..)).))))...

Structure
uac    c  --    U  U           C   u g a 
   ugcc UC  GGCU CU UACAGUGCUGC UUG u c u
   |||| ||  |||| || ||||||||||| ||| | |  
   acgg AG  UCGG GA AUGUUACGACG Aac a g a
guu    a  UA    -  C           -   u g u 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context
chr6: 166809198-166809275 [-]

Database links

Mature mml-miR-103-3p

Accession MIMAT0002447
Description Macaca mulatta mml-miR-103-3p mature miRNA
Sequence 48 - AGCAGCAUUGUACAGGGCUAUGA - 70
Evidence not_experimental
Database links
Predicted targets

Mature mml-miR-103-5p

Accession MIMAT0026582
Description Macaca mulatta mml-miR-103-5p mature miRNA
Sequence 9 - UCGGCUUCUUUACAGUGCUGCCUUG - 33
Evidence experimental
Illumina [3]

References

  1. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68

  2. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  3. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45