miRBase entry: mml-mir-15b

Stem-loop mml-mir-15b


Accession
MI0002496
Description
Macaca mulatta mml-mir-15b precursor miRNA
Gene family
MIPF0000006; mir-15

Literature search
1 open access papers mention mml-mir-15b
(3 sentences)

Sequence

4491 reads, 81 reads per million, 9 experiments
uugaggccuuaaaguacugUAGCAGCACAUCAUGGUUUACAuacuacagucaagaugCGAAUCAUUAUUUGCUGCUCUAgaaauuuaaggaaauucau
.((((.(((((((...(((.(((((((.((.(((((((.(((.((.......))))).))))))).)).))))))).)))...)))))))...)))).

Structure
u    --g       gua   U       C  C       A   a  ac 
 ugag   ccuuaaa   cug AGCAGCA AU AUGGUUU CAu cu  a
 ||||   |||||||   ||| ||||||| || ||||||| ||| ||  g
 acuu   ggaauuu   gAU UCGUCGU UA UACUAAG gua ga  u
u    aaa       aaa   C       U  U       C   -  ac 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr2: 134308684-134308781 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from mml-mir-15b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mml-miR-15b-5p

Accession MIMAT0002207
Description Macaca mulatta mml-miR-15b-5p mature miRNA
Sequence 20 - UAGCAGCACAUCAUGGUUUACA - 41
Evidence experimental
Illumina [2]
Database links
Predicted targets

Mature mml-miR-15b-3p

Accession MIMAT0026562
Description Macaca mulatta mml-miR-15b-3p mature miRNA
Sequence 58 - CGAAUCAUUAUUUGCUGCUCUA - 79
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  2. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45