Stem-loop hsa-mir-487a

Accession

MI0002471

Symbol

HGNC: MIR487A

Description

Homo sapiens hsa-mir-487a precursor miRNA

Gene family

MIPF0000018; mir-154

Literature search

14 open access papers mention hsa-mir-487a
(32 sentences)

Sequence

1834 reads, 33 reads per million, 48 experiments

gguacuugaagaGUGGUUAUCCCUGCUGUGUUCGcuuaauuuaugacgAAUCAUACAGGGACAUCCAGUUuuucaguauc
((((((.(((((.(((...((((((.(((((((((.........).)))).))))))))))...))).))))).))))))

Structure

      u     G   UUA      C    -    - uua 
gguacu gaaga UGG   UCCCUG UGUG UUCG c   a
|||||| ||||| |||   |||||| |||| |||| |   u
cuauga uuuUU ACC   AGGGAC AUAC AAgc g   u
      c     G   UAC      -    U    a uau 

Annotation confidence High

Genome context

chr14: 101052446-101052525 [+]

Clustered miRNAs

16 other miRNAs are < 10 kb from hsa-mir-487a

Disease association

hsa-mir-487a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-487a-3p

• Accession: MIMAT0002178
• Description: Homo sapiens hsa-miR-487a-3p mature miRNA
• Sequence: 49 - AAUCAUACAGGGACAUCCAGUU - 70
• Evidence: experimental ; cloned [1-3], Northern [1], Illumina [4]

Mature hsa-miR-487a-5p

• Accession: MIMAT0026559
• Description: Homo sapiens hsa-miR-487a-5p mature miRNA
• Sequence: 13 - GUGGUUAUCCCUGCUGUGUUCG - 34
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15978578
   Identification of human fetal liver miRNAs by a novel method
   "Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X"
   "FEBS Lett (2005) 579:3849-3854


3. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267


4. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45