miRBase entry: mmu-mir-365-2

Stem-loop mmu-mir-365-2


Accession
MI0001645
Symbol
MGI: Mir365-2
Description
Mus musculus mmu-mir-365-2 precursor miRNA
Gene family
MIPF0000061; mir-365

Literature search
24 open access papers mention mmu-mir-365-2
(92 sentences)

Sequence

28156 reads, 421 reads per million, 105 experiments
agagugaucaaggacagcaagaaaaaugAGGGACUUUCAGGGGCAGCUGUGuuuccugacucagucaUAAUGCCCCUAAAAAUCCUUAUuguucuugcagugugcaucggag
....((((...(.((.(((((((.((((((((..(((.(((((((((((.(((....))).)))).....))))))).))).)))))))).))))))).)).)..))))...

Structure
agag    caa g  a       a        AC   C       -----    U   u 
    ugau   g ac gcaagaa aaugAGGG  UUU AGGGGCA     GCUG Guu c
    ||||   | || ||||||| ||||||||  ||| |||||||     |||| |||  
    gcua   u ug cguucuu uUAUUCCU  AAA UCCCCGU     ugac cag c
-gag    -cg g  a       g        -A   A       AAUac    u   u 


Annotation confidence High
Do you think this miRNA is real?
Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR190. The sequence is unrelated to mammalian mir-190 (MIR:MI0000486).

Genome context
chr11: 79726400-79726511 [+]

Database links

Mature mmu-miR-365-3p

Accession MIMAT0000711
Description Mus musculus mmu-miR-365-3p mature miRNA
Sequence 68 - UAAUGCCCCUAAAAAUCCUUAU - 89
Evidence experimental
cloned [2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-365-2-5p

Accession MIMAT0017179
Description Mus musculus mmu-miR-365-2-5p mature miRNA
Sequence 29 - AGGGACUUUCAGGGGCAGCUGUG - 51
Evidence experimental
Illumina [4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  3. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  4. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345