miRBase entry: rno-mir-181a-1

Stem-loop rno-mir-181a-1


Accession
MI0000953
Description
Rattus norvegicus rno-mir-181a-1 precursor miRNA
Gene family
MIPF0000007; mir-181

Literature search
63 open access papers mention rno-mir-181a-1
(297 sentences)

Sequence

36319460 reads, 27213 reads per million, 509 experiments
agguugcuucagugAACAUUCAACGCUGUCGGUGAGUuuggaauucaaauaaaaACCAUCGACCGUUGAUUGUACCcuauagcuaaccauuaucuacucc
.(((((((..((.(.(((.((((((..(((((((.((((.............))))))))))))))))).))).).))..))).))))............

Structure
-----------a    -   uc  u A   U      CU       A    ggaau 
            gguu gcu  ag g ACA UCAACG  GUCGGUG GUuu     u
            |||| |||  || | ||| ||||||  ||||||| ||||     c
            ccaa cga  uc C UGU AGUUGC  CAGCUAC CAaa     a
ccucaucuauua    u   ua  C A   U      --       -    aauaa 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chr13: 54952742-54952841 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from rno-mir-181a-1
Name Accession Chromosome Start End Strand Confidence




Database links

Mature rno-miR-181a-5p

Accession MIMAT0000858
Description Rattus norvegicus rno-miR-181a-5p mature miRNA
Sequence 15 - AACAUUCAACGCUGUCGGUGAGU - 37
Evidence experimental
cloned [3-4], SOLiD [4]

Mature rno-miR-181a-1-3p

Accession MIMAT0000884
Description Rattus norvegicus rno-miR-181a-1-3p mature miRNA
Sequence 55 - ACCAUCGACCGUUGAUUGUACC - 76
Evidence experimental
cloned [1], SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  3. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68

  4. PubMed ID: 17805466
    Cloning and identification of novel microRNAs from rat hippocampus
    "He X, Zhang Q, Liu Y, Pan X"
    "Acta Biochim Biophys Sin (Shanghai) (2007) 39:708-714