miRBase entry: rno-mir-185

Stem-loop rno-mir-185


Accession
MI0000930
Description
Rattus norvegicus rno-mir-185 precursor miRNA
Gene family
MIPF0000202; mir-185

Literature search
14 open access papers mention rno-mir-185
(175 sentences)

Sequence

36190 reads, 1155 reads per million, 486 experiments
gggggugagggauUGGAGAGAAAGGCAGUUCCUGAugguccccucccaggggcuggcUUUCCUCUGGUCCUUCUCUccca
(((((.((((((((((((.(((((.(((((((((..((......))))))))))).))))))))))))))))).))))).

Structure
-     u            A     G         Au  uc 
 ggggg gagggauUGGAG GAAAG CAGUUCCUG  gg  c
 ||||| |||||||||||| ||||| |||||||||  ||   
 cccUC CUUCCUGGUCUC CUUUc gucggggac  cc  c
a     U            -     g         --  uc 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr11: 86812702-86812781 [+]

Database links

Mature rno-miR-185-5p

Accession MIMAT0000862
Description Rattus norvegicus rno-miR-185-5p mature miRNA
Sequence 14 - UGGAGAGAAAGGCAGUUCCUGA - 35
Evidence experimental
cloned [1-3], SOLiD [4]

Mature rno-miR-185-3p

Accession MIMAT0017142
Description Rattus norvegicus rno-miR-185-3p mature miRNA
Sequence 58 - UUUCCUCUGGUCCUUCUCU - 76
Evidence experimental
SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68