miRBase entry: rno-mir-30b

Stem-loop rno-mir-30b


Accession
MI0000868
Description
Rattus norvegicus rno-mir-30b precursor miRNA
Gene family
MIPF0000005; mir-30

Literature search
63 open access papers mention rno-mir-30b
(421 sentences)

Sequence

1144717 reads, 1054 reads per million, 504 experiments
ccgaguuucaguucaUGUAAACAUCCUACACUCAGCUgucauacaugaguuggCUGGGAUGUGGAUGUUUACGUCagcugucuugga
(((((...(((((.((((((((((((.((((((((((.(((....)))...))))))).))))))))))))))).))))).))))).

Structure
-     uuu     c            U   -       --g   u 
 ccgag   caguu aUGUAAACAUCC ACA CUCAGCU   uca a
 |||||   ||||| |||||||||||| ||| |||||||   |||  
 gguuc   gucga UGCAUUUGUAGG UGU GGGUCgg   agu c
a     --u     C            -   A       uug   a 


Annotation confidence High
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Comments
Landgraf et al. show that miRNA sequences from both arms of this hairpin precursor are similarly expressed [4].

Genome context
Unknown

Database links

Mature rno-miR-30b-5p

Accession MIMAT0000806
Description Rattus norvegicus rno-miR-30b-5p mature miRNA
Sequence 16 - UGUAAACAUCCUACACUCAGCU - 37
Evidence experimental
cloned [1-4], Northern [1,3], SOLiD [5]

Mature rno-miR-30b-3p

Accession MIMAT0004721
Description Rattus norvegicus rno-miR-30b-3p mature miRNA
Sequence 54 - CUGGGAUGUGGAUGUUUACGUC - 75
Evidence experimental
cloned [4], SOLiD [5]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 14691248
    Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
    "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
    "Proc Natl Acad Sci U S A (2004) 101:360-365

  4. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  5. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68