miRBase entry: rno-mir-26a

Stem-loop rno-mir-26a


Accession
MI0000857
Description
Rattus norvegicus rno-mir-26a precursor miRNA
Gene family
MIPF0000043; mir-26

Literature search
54 open access papers mention rno-mir-26a
(455 sentences)

Sequence

37435645 reads, 34513 reads per million, 514 experiments
aaggccguggccuugUUCAAGUAAUCCAGGAUAGGCUgugcaggucccaaggggCCUAUUCUUGGUUACUUGCACggggacgcgggccug
.((((((((.((((((.(((((((((.((((((((((.(...........).)))))))))).))))))))).)))))).))).))))).

Structure
a     -   g      U         C          g gcag 
 aggcc gug ccuugU CAAGUAAUC AGGAUAGGCU u    g
 ||||| ||| |||||| ||||||||| |||||||||| |    u
 uccgg cgc ggggCA GUUCAUUGG UCUUAUCCgg g    c
g     g   a      C         U          g aacc 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr8: 127714441-127714530 [+]

Database links

Mature rno-miR-26a-5p

Accession MIMAT0000796
Description Rattus norvegicus rno-miR-26a-5p mature miRNA
Sequence 16 - UUCAAGUAAUCCAGGAUAGGCU - 37
Evidence experimental
cloned [1-3], SOLiD [4]

Mature rno-miR-26a-3p

Accession MIMAT0017100
Description Rattus norvegicus rno-miR-26a-3p mature miRNA
Sequence 55 - CCUAUUCUUGGUUACUUGCAC - 75
Evidence experimental
SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 17805466
    Cloning and identification of novel microRNAs from rat hippocampus
    "He X, Zhang Q, Liu Y, Pan X"
    "Acta Biochim Biophys Sin (Shanghai) (2007) 39:708-714