miRBase entry: mmu-mir-377

Stem-loop mmu-mir-377


Accession
MI0000794
Symbol
MGI: Mir377
Description
Mus musculus mmu-mir-377 precursor miRNA
Gene family
MIPF0000018; mir-154

Literature search
22 open access papers mention mmu-mir-377
(112 sentences)

Sequence

27397 reads, 669 reads per million, 72 experiments
ugagcAGAGGUUGCCCUUGGUGAAUUCgcuuuauugauguugaAUCACACAAAGGCAACUUUUGUuug
.((((((((((((((.(((((((.(((((.........).)))))))).))).)))))))))))))).

Structure
u              C   -    A    - uuu 
 gagcAGAGGUUGCC UUG GUGA UUCg c   a
 |||||||||||||| ||| |||| |||| |   u
 uuUGUUUUCAACGG AAC CACU Aagu g   u
g              A   A    -    u uag 


Annotation confidence High
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Genome context
chr12: 109740510-109740577 [+]
Clustered miRNAs
13 other miRNAs are < 10 kb from mmu-mir-377
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-377-5p

Accession MIMAT0017079
Description Mus musculus mmu-miR-377-5p mature miRNA
Sequence 6 - AGAGGUUGCCCUUGGUGAAUUC - 27
Evidence experimental
Illumina [5]
Database links
Predicted targets

Mature mmu-miR-377-3p

Accession MIMAT0000741
Description Mus musculus mmu-miR-377-3p mature miRNA
Sequence 44 - AUCACACAAAGGCAACUUUUGU - 65
Evidence experimental
cloned [1-3], Illumina [4-5]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  5. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267