miRBase entry: hsa-mir-375

Stem-loop hsa-mir-375


Accession
MI0000783
Symbol
HGNC: MIR375
Description
Homo sapiens hsa-mir-375 precursor miRNA
Gene family
MIPF0000114; mir-375

Literature search
256 open access papers mention hsa-mir-375
(1718 sentences)

Sequence

258390 reads, 1004 reads per million, 138 experiments
ccccGCGACGAGCCCCUCGCACAAACCggaccugagcguUUUGUUCGUUCGGCUCGCGUGAggc
.((((((.((((((...((.(((((.((........)).))))).))...)))))))))).)).

Structure
c  -    A      CCU  C     C  gac 
 cc cGCG CGAGCC   CG ACAAA Cg   c
 || |||| ||||||   || ||||| ||    
 gg GUGC GCUCGG   GC UGUUU gc   u
c  A    -      CUU  U     u  gag 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chr2: 219001645-219001708 [-]

Disease association
hsa-mir-375 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-375-3p

Accession MIMAT0000728
Description Homo sapiens hsa-miR-375-3p mature miRNA
Sequence 40 - UUUGUUCGUUCGGCUCGCGUGA - 61
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-375-5p

Accession MIMAT0037313
Description Homo sapiens hsa-miR-375-5p mature miRNA
Sequence 5 - GCGACGAGCCCCUCGCACAAACC - 27
Evidence not_experimental

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230