miRBase entry: hsa-mir-371a

Stem-loop hsa-mir-371a


Accession
MI0000779
Symbol
HGNC: MIR371A
Description
Homo sapiens hsa-mir-371a precursor miRNA
Gene family
MIPF0000068; mir-290

Literature search
78 open access papers mention hsa-mir-371a
(493 sentences)

Sequence

124 reads, 12 reads per million, 22 experiments
guggcACUCAAACUGUGGGGGCACUuucugcucucuggugaAAGUGCCGCCAUCUUUUGAGUGUuac
((((((((((((..((((.(((((((((.(((....)))))))))))).))))..))))))))))))

Structure
            CU    G         u   c 
guggcACUCAAA  GUGG GGCACUuuc gcu u
||||||||||||  |||| ||||||||| |||  
cauUGUGAGUUU  UACC CCGUGAAag ugg c
            UC    G         -   u 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Human miR-371 (MIR:MI0000779), miR-372 (MIR:MI0000780) and miR-373 (MIR:MI0000781) are clustered within 1.1kb on chromosome 19. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chr19: 53787675-53787741 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from hsa-mir-371a
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-371a is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-371a-5p

Accession MIMAT0004687
Description Homo sapiens hsa-miR-371a-5p mature miRNA
Sequence 6 - ACUCAAACUGUGGGGGCACU - 25
Evidence experimental
cloned [2]

Mature hsa-miR-371a-3p

Accession MIMAT0000723
Description Homo sapiens hsa-miR-371a-3p mature miRNA
Sequence 42 - AAGUGCCGCCAUCUUUUGAGUGU - 64
Evidence experimental
cloned [1-2], Northern [1]

References

  1. PubMed ID: 15183728
    Human embryonic stem cells express a unique set of microRNAs
    "Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS"
    "Dev Biol (2004) 270:488-498

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414