Stem-loop sequence mmu-mir-124-2

AccessionMI0000717 (change log)
Previous IDsmmu-mir-124a-2
Symbol MGI:Mir124a-2
DescriptionMus musculus miR-124-2 stem-loop
Gene family MIPF0000021; mir-124
Literature search

227 open access papers mention mmu-mir-124-2
(2506 sentences)

   a     au   ----  a         cc        a   ga        uaau 
5'  ucaag  cag    ag cucugcucu  guguucac gcg  ccuugauu    g
    |||||  |||    || |||||||||  |||||||| |||  ||||||||    u
3'  aguuc  guc    uc gaggcgaga  cguaagug cgc  ggaauuaa    c
   a     ac   ggca  c         ac        g   ac        caua 
Get sequence
Deep sequencing
1179477 reads, 6.85e+03 reads per million, 81 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

miR-124 was cloned from mouse brain [1] and embryonic stem cells [2] by independent groups. There are 3 predicted precursor hairpin sequences: mir-124-1 (MI0000716) on chromosome 14, mir-124-2 (MI0000717) on chromosome 3, and mir-124-3 (previously known as miR-124 here, MI0000150) on chromosome 2. All have closely related predicted human homologues (MI0000443, MI0000444 and MI0000445). Lagos-Quintana et al. also report a mature miRNA sequence miR-124b, with a G insertion at position 12 [1]. miR-124b is not found in either the mouse or human genome assemblies.

Genome context
Coordinates (GRCm38; GCA_000001635.2) Overlapping transcripts
chr3: 17795662-17795770 [+]
Clustered miRNAs
< 10kb from mmu-mir-124-2
mmu-mir-124-2chr3: 17795662-17795770 [+]
mmu-mir-124bchr3: 17795685-17795741 [-]
Database links

Mature sequence mmu-miR-124-5p

Accession MIMAT0004527
Previous IDsmmu-miR-124*

25 - 


 - 46

Get sequence
Deep sequencing8477 reads, 35 experiments
Evidence experimental; cloned [4], Illumina [5-6]
Database links
Predicted targets

Mature sequence mmu-miR-124-3p

Accession MIMAT0000134
Previous IDsmmu-miR-124a;mmu-miR-124

62 - 


 - 81

Get sequence
Deep sequencing3529575 reads, 78 experiments
Evidence experimental; cloned [1-4], Illumina [5-6]
Database links
Predicted targets


PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).