miRBase entry: mmu-mir-103-1

Stem-loop mmu-mir-103-1


Accession
MI0000587
Symbol
MGI: Mir103-1
Description
Mus musculus mmu-mir-103-1 precursor miRNA
Gene family
MIPF0000024; mir-103

Literature search
99 open access papers mention mmu-mir-103-1
(437 sentences)

Sequence

6142774 reads, 16701 reads per million, 107 experiments
uucuuacugcccucGGCUUCUUUACAGUGCUGCCUUGuugcauauggaucaAGCAGCAUUGUACAGGGCUAUGAaggcauugagac
.(((((.((((.((((((.((.(((((((((((.(((.(.(....).).)))))))))))))).))))))..)).)))).))))).

Structure
u     c    c  --    U  U           C   u g a 
 ucuua ugcc uc  GGCU CU UACAGUGCUGC UUG u c u
 ||||| |||| ||  |||| || ||||||||||| ||| | |  
 agagu acgg AG  UCGG GA AUGUUACGACG Aac a g a
c     u    a  UA    -  C           -   u g u 


Annotation confidence High
Do you think this miRNA is real?
Comments
This miRNA sequence was predicted based on homology to a verified miRNA from human [1], and subsequently verified by cloning [2-4].

Genome context
chr11: 35782396-35782481 [+]

Database links

Mature mmu-miR-103-1-5p

Accession MIMAT0017024
Description Mus musculus mmu-miR-103-1-5p mature miRNA
Sequence 15 - GGCUUCUUUACAGUGCUGCCUUG - 37
Evidence experimental
454 [6], Illumina [7]
Database links
Predicted targets

Mature mmu-miR-103-3p

Accession MIMAT0000546
Description Mus musculus mmu-miR-103-3p mature miRNA
Sequence 52 - AGCAGCAUUGUACAGGGCUAUGA - 74
Evidence experimental
cloned [2-4], Illumina [5,7]
Database links
Predicted targets

References

  1. PubMed ID: 12554860
    Numerous microRNPs in neuronal cells containing novel microRNAs
    "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
    "RNA (2003) 9:180-186

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 11914277
    miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
    "Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G"
    "Genes Dev (2002) 16:720-728

  4. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  5. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  6. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  7. PubMed ID: 20668074
    Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
    "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
    "J Virol (2010) 84:10266-10275