Stem-loop sequence mmu-mir-34a

AccessionMI0000584 (change log)
Previous IDsmmu-mir-172;mmu-mir-34c
Symbol MGI:Mir34a
DescriptionMus musculus miR-34a stem-loop
Gene family MIPF0000039; mir-34
Literature search

388 open access papers mention mmu-mir-34a
(5429 sentences)

   c   c    -    a    uu        -   a          --gug   a 
5'  cag ugug agua uucu  ggcagugu cuu gcugguuguu     agu u
    ||| |||| |||| ||||  |||||||| ||| ||||||||||     |||  
3'  guu acac ucgu aaga  ccgucaua gaa cgacuaacga     ucg u
   u   -    g    g    uc        u   -          aggaa   a 
Get sequence
Deep sequencing
57713 reads, 307 reads per million, 106 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

Houbaviy et al. cloned this miRNA from embryonic stem cells and named it miR-172 [1]. This sequence is homologous to human miR-34a (MI0000268), and so is renamed miR-34a here. This sequence is not related to miR172 from plants (MI0000215 and MI0000216). The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context
Coordinates (GRCm38; GCA_000001635.2) Overlapping transcripts
chr4: 150068454-150068555 [+]
Database links

Mature sequence mmu-miR-34a-5p

Accession MIMAT0000542
Previous IDsmmu-miR-34a

20 - 


 - 41

Get sequence
Deep sequencing55682 reads, 104 experiments
Evidence experimental; cloned [1,3], Illumina [4,6]
Database links
Predicted targets

Mature sequence mmu-miR-34a-3p

Accession MIMAT0017022
Previous IDsmmu-miR-34a*

64 - 


 - 84

Get sequence
Deep sequencing1895 reads, 82 experiments
Evidence experimental; 454 [5], Illumina [6]
Database links
Predicted targets


PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).