Stem-loop sequence mmu-mir-93

Accession

MI0000581 (change log)

Symbol

MGI:Mir93

Description

Mus musculus miR-93 stem-loop

Gene family

MIPF0000001; mir-17

Literature search

104 open access papers mention mmu-mir-93
(1041 sentences)

Stem-loop

   a   a         -ca       -     u    g   u  aau 
5'  guc ugggggcuc   aagugcu guucg gcag uag gu   u
    ||| |||||||||   ||||||| ||||| |||| ||| ||   a
3'  cag acccccgag   uucacga cgagu cguc auc ca   c
   a   g         ccc       u     -    -   -  guc 

Deep sequencing

589996 reads, 2.02e+03 reads per million, 108 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr5: 138165523-138165610 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000054336 ; Mcm7-010; exon 1

  OTTMUST00000054328 ; Mcm7-002; intron 8

  OTTMUST00000054327 ; Mcm7-001; intron 13

  ENSMUST00000125316 ; Mcm7-010; exon 1

  ENSMUST00000148879 ; Mcm7-002; intron 8

  ENSMUST00000000505 ; Mcm7-001; intron 13

Clustered miRNAs

< 10kb from mmu-mir-93

• mmu-mir-106b: chr5: 138165737-138165818 [-]
• mmu-mir-93: chr5: 138165523-138165610 [-]
• mmu-mir-25: chr5: 138165321-138165404 [-]

Database links

• EntrezGene:Mirn93
• MGI:Mir93
• RNAcentral:URS000075C178_10090
• miRBase Tracker:MI0000581

Mature sequence mmu-miR-93-5p

• Accession: MIMAT0000540
• Previous IDs: mmu-miR-93
• Sequence: 15 - caaagugcuguucgugcagguag - 37
• Deep sequencing: 584962 reads, 107 experiments
• Evidence: experimental; cloned [1-3], Northern [1], Illumina [4-5]
• Database links:
  • RNAcentral:URS0000149452_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-93-5p
  • miRDB:mmu-miR-93-5p
  • microrna.org:mmu-miR-93-5p

Mature sequence mmu-miR-93-3p

• Accession: MIMAT0004636
• Previous IDs: mmu-miR-93*
• Sequence: 54 - acugcugagcuagcacuucccg - 75
• Deep sequencing: 4879 reads, 106 experiments
• Evidence: experimental; cloned [3], Illumina [4-5]
• Database links:
  • RNAcentral:URS00000FB1B1_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-93-3p
  • miRDB:mmu-miR-93-3p
  • microrna.org:mmu-miR-93-3p

References

1. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).