Stem-loop sequence hsa-mir-193a

Accession

MI0000487 (change log)

Previous IDs

hsa-mir-193

Symbol

HGNC:MIR193A

Description

Homo sapiens miR-193a stem-loop

Gene family

MIPF0000082; mir-193

Literature search

148 open access papers mention hsa-mir-193a
(983 sentences)

Stem-loop

   cgaggau   a             u     cg   g  a   gggu 
5'        ggg gcugagggcuggg cuuug  ggc ag uga    g
          ||| ||||||||||||| |||||  ||| || |||     
3'        ccc cggcucuugaccc gaaac  ccg uc acu    u
   ------g   c             u     au   g  a   aggc 

Deep sequencing

118699 reads, 540 reads per million, 159 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr17: 31559996-31560083 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000256378 ; ASIC2-001; intron 1

  OTTHUMT00000447552 ; ASIC2-003; intron 1

  OTTHUMT00000447553 ; ASIC2-004; intron 1

  OTTHUMT00000256379 ; ASIC2-002; intron 2

  ENST00000225823 ; ASIC2-001; intron 1

  ENST00000359872 ; ASIC2-003; intron 1

  ENST00000579816 ; ASIC2-004; intron 1

  ENST00000448983 ; ASIC2-002; intron 2

Database links

• EntrezGene:MIR193A
• HGNC:MIR193A
• RNAcentral:URS000075EC4B_9606
• miRBase Tracker:MI0000487

Mature sequence hsa-miR-193a-5p

• Accession: MIMAT0004614
• Sequence: 21 - ugggucuuugcgggcgagauga - 42
• Deep sequencing: 46220 reads, 156 experiments
• Evidence: experimental; cloned [2-3]
• Database links:
  • RNAcentral:URS0000367985_9606
• Predicted targets:
  • TargetMiner:hsa-miR-193a-5p
  • TargetScanVert:hsa-miR-193a-5p
  • miRDB:hsa-miR-193a-5p
  • microrna.org:hsa-miR-193a-5p

Mature sequence hsa-miR-193a-3p

• Accession: MIMAT0000459
• Previous IDs: hsa-miR-193;hsa-miR-193a
• Sequence: 55 - aacuggccuacaaagucccagu - 76
• Deep sequencing: 72316 reads, 158 experiments
• Evidence: experimental; cloned [2-3]
• Database links:
  • RNAcentral:URS00005DBAF3_9606
• Predicted targets:
  • TargetMiner:hsa-miR-193a-3p
  • TargetScanVert:hsa-miR-193a-3p
  • miRDB:hsa-miR-193a-3p
  • microrna.org:hsa-miR-193a-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).