Accession
MI0000478
Symbol
HGNC:
MIR149
Description
Homo sapiens
hsa-mir-149 precursor miRNA
Gene family
MIPF0000274;
mir-149
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR149 is a gene located at 2q37.3, consisting of one exon that codes for MIR149 and exhibits polymorphisms [PMC9956572]. The expression of miR-149 and the EphB3 gene in SW1116 and HCT116 cells is influenced by Form [PMC5983960]. However, the mechanism by which MIR149 regulates the expression of MMP and cyclin D remains unknown, requiring further investigation [PMC5983960].
Literature search
114 open access papers mention hsa-mir-149
(820 sentences)
(820 sentences)
Sequence
41611
reads,
225
reads per million, 121 experiments
gccggcgcccgagcUCUGGCUCCGUGUCUUCACUCCCgugcuuguccgaggagggAGGGAGGGACGGGGGCUGUGCuggggcagcugga
.(((((((((.(((.(.(.((((((.(((((.(((((.(.(((....))).))))))))))).)))))).).).))).)))).))))).
.(((((((((.(((.(.(.((((((.(((((.(((((.(.(((....))).))))))))))).)))))).).).))).)))).))))).
Structure
g - g U U G G A g g g ccggc gccc agc C G CUCCGU UCUUC CUCCC u cuu u ||||| |||| ||| | | |||||| ||||| ||||| | ||| ggucg cggg uCG G C GGGGCA GGAGG GAggg a gag c a a g U U G G - - g c
Annotation confidence
High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].
Genome context
chr2: 240456001-240456089 [+]
Disease association
hsa-mir-149 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-149-5p
| Accession | MIMAT0000450 |
| Description | Homo sapiens hsa-miR-149-5p mature miRNA |
| Sequence | 15 - UCUGGCUCCGUGUCUUCACUCCC - 37 |
| Evidence |
experimental
cloned [2-3] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-149-3p
| Accession | MIMAT0004609 |
| Description | Homo sapiens hsa-miR-149-3p mature miRNA |
| Sequence | 56 - AGGGAGGGACGGGGGCUGUGC - 76 |
| Evidence |
experimental
cloned [3] |
| Database links |
|
| Predicted targets |
|
References
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