miRBase entry: dme-mir-306

Stem-loop dme-mir-306


Accession
MI0000414
Description
Drosophila melanogaster dme-mir-306 precursor miRNA
Gene family
MIPF0000313; mir-306

Literature search
5 open access papers mention dme-mir-306
(18 sentences)

Sequence

394168 reads, 12857 reads per million, 49 experiments
guccacucgauggcUCAGGUACUUAGUGACUCUCAAugcuuuugacauuuuGGGGGUCACUCUGUGCCUGUGCugccagugggac
.((((((.(.((((.(((((((..(((((((((((((((....).)))..)))))))))))..))))))).))))).))))))..

Structure
-g      c a    U       UU           --   - u 
  uccacu g uggc CAGGUAC  AGUGACUCUCA  Aug c u
  |||||| | |||| |||||||  |||||||||||  ||| |  
  ggguga c guCG GUCCGUG  UCACUGGGGGu  uac g u
ca      c -    U       UC           uu   a u 


Annotation confidence High
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Comments
miR-306 was identified and ends mapped by cloning. Reference [1] also identified a less predominantly expressed miR from the opposite arm of the precursor, designated miR-306* here

Genome context
chr2L: 16698404-16698488 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from dme-mir-306
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-306-5p

Accession MIMAT0000393
Description Drosophila melanogaster dme-miR-306-5p mature miRNA
Sequence 15 - UCAGGUACUUAGUGACUCUCAA - 36
Evidence experimental
cloned [1], 454 [2-3], Illumina [3]
Database links
Predicted targets

Mature dme-miR-306-3p

Accession MIMAT0000394
Description Drosophila melanogaster dme-miR-306-3p mature miRNA
Sequence 52 - GGGGGUCACUCUGUGCCUGUGC - 73
Evidence experimental
cloned [1], 454 [2-3], Illumina [3]
Database links

References

  1. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  2. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  3. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879