Stem-loop sequence mmu-mir-291a

Accession

MI0000389 (change log)

Previous IDs

mmu-mir-291

Symbol

MGI:Mir291a

Description

Mus musculus miR-291a stem-loop

Gene family

MIPF0000068; mir-290

Literature search

24 open access papers mention mmu-mir-291a
(92 sentences)

Stem-loop

            c   -  u            c  c    gagc 
5' ccuauguag ggc ca caaaguggaggc cu ucuu    c
   ||||||||| ||| || |||||||||||| || ||||     
3' ggguacguc ccg gu guuucaccuucg ga agag    u
            a   u  -            u  a    uaag 

Deep sequencing

70039 reads, 700 reads per million, 48 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr7: 3218919-3219000 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-291a

• mmu-mir-290a: chr7: 3218626-3218708 [+]
• mmu-mir-290b: chr7: 3218638-3218695 [-]
• mmu-mir-291a: chr7: 3218919-3219000 [+]
• mmu-mir-292a: chr7: 3219189-3219270 [+]
• mmu-mir-292b: chr7: 3219198-3219259 [-]
• mmu-mir-291b: chr7: 3219482-3219560 [+]
• mmu-mir-293: chr7: 3220343-3220422 [+]
• mmu-mir-294: chr7: 3220641-3220724 [+]
• mmu-mir-295: chr7: 3220773-3220841 [+]

Database links

• EntrezGene:Mir291a
• MGI:Mir291a
• RNAcentral:URS000075ADEE_10090
• miRBase Tracker:MI0000389

Mature sequence mmu-miR-291a-5p

• Accession: MIMAT0000367
• Previous IDs: mmu-miR-291-5p
• Sequence: 14 - caucaaaguggaggcccucucu - 35
• Deep sequencing: 43451 reads, 37 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00002D7227_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-291a-5p
  • miRDB:mmu-miR-291a-5p
  • microrna.org:mmu-miR-291a-5p

Mature sequence mmu-miR-291a-3p

• Accession: MIMAT0000368
• Previous IDs: mmu-miR-291-3p
• Sequence: 50 - aaagugcuuccacuuugugugc - 71
• Deep sequencing: 26583 reads, 37 experiments
• Evidence: experimental; cloned [1-2], Northern [1], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000128E26_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-291a-3p
  • miRDB:mmu-miR-291a-3p
  • microrna.org:mmu-miR-291a-3p

References

1. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).