Stem-loop sequence mmu-mir-185

Accession

MI0000227 (change log)

Symbol

MGI:Mir185

Description

Mus musculus miR-185 stem-loop

Gene family

MIPF0000202; mir-185

Literature search

36 open access papers mention mmu-mir-185
(224 sentences)

Stem-loop

         ug   a     g         au  uc 
5' agggau  gag gaaag caguuccug  gg  c
   ||||||  ||| ||||| |||||||||  ||   
3' uuccug  cuc cuuuc gucggggac  cc  c
         gu   -     g         --  uc 

Deep sequencing

603093 reads, 1.26e+03 reads per million, 105 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr16: 18327401-18327465 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000064221 ; RP23-47O21.5-001; intron 1

  OTTMUST00000064224 ; RP23-47O21.5-004; intron 1

  OTTMUST00000064868 ; RP23-47O21.5-010; intron 1

  OTTMUST00000064223 ; RP23-47O21.5-003; intron 1

  ENSMUST00000115628 ; Tango2-001; intron 1

  ENSMUST00000125287 ; Tango2-004; intron 1

  ENSMUST00000130752 ; Tango2-010; intron 1

  ENSMUST00000134385 ; Tango2-003; intron 1

  ENSMUST00000083530 ; Mir185-201; exon 1

Database links

• EntrezGene:Mir185
• MGI:Mir185
• RNAcentral:URS000075B989_10090
• miRBase Tracker:MI0000227

Mature sequence mmu-miR-185-5p

• Accession: MIMAT0000214
• Previous IDs: mmu-miR-185
• Sequence: 7 - uggagagaaaggcaguuccuga - 28
• Deep sequencing: 600847 reads, 105 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00004176D4_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-185-5p
  • miRDB:mmu-miR-185-5p
  • microrna.org:mmu-miR-185-5p

Mature sequence mmu-miR-185-3p

• Accession: MIMAT0016996
• Previous IDs: mmu-miR-185*
• Sequence: 41 - aggggcuggcuuuccucuggu - 61
• Deep sequencing: 2246 reads, 96 experiments
• Evidence: experimental; Illumina [4]
• Database links:
  • RNAcentral:URS00004A4E27_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-185-3p
  • miRDB:mmu-miR-185-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).