Stem-loop sequence mmu-mir-149

Accession

MI0000171 (change log)

Symbol

MGI:Mir149

Description

Mus musculus miR-149 stem-loop

Gene family

MIPF0000274; mir-149

Literature search

30 open access papers mention mmu-mir-149
(319 sentences)

Stem-loop

      u   g      g     a     g g   g 
5' ggc cug cuccgu ucuuc cuccc u uuu u
   ||| ||| |||||| ||||| ||||| | |||  
3' ucg ggc ggggca ggagg gaggg a gag c
      u   g      g     -     - g   c 

Deep sequencing

66960 reads, 122 reads per million, 95 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr1: 92850378-92850443 [+]
• Overlapping transcripts:

  sense

  ENSMUST00000045970 ; Gpc1-201; intron 1

Database links

• EntrezGene:Mir149
• MGI:Mir149
• RNAcentral:URS000075E3AD_10090
• miRBase Tracker:MI0000171

Mature sequence mmu-miR-149-5p

• Accession: MIMAT0000159
• Previous IDs: mmu-miR-149
• Sequence: 4 - ucuggcuccgugucuucacuccc - 26
• Deep sequencing: 66111 reads, 81 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00001C770D_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-149-5p
  • miRDB:mmu-miR-149-5p
  • microrna.org:mmu-miR-149-5p

Mature sequence mmu-miR-149-3p

• Accession: MIMAT0016990
• Previous IDs: mmu-miR-149*
• Sequence: 44 - gagggagggacgggggcggugc - 65
• Deep sequencing: 246 reads, 59 experiments
• Evidence: experimental; Illumina [4]
• Database links:
  • RNAcentral:URS0000243B8C_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-149-3p
  • miRDB:mmu-miR-149-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).