Stem-loop sequence mmu-mir-130a

Accession

MI0000156 (change log)

Previous IDs

mmu-mir-130

Symbol

MGI:Mir130a

Description

Mus musculus miR-130a stem-loop

Gene family

MIPF0000034; mir-130

Literature search

90 open access papers mention mmu-mir-130a
(632 sentences)

Stem-loop

   -ga        c      ug  a  --  - ua 
5'    gcucuuuu acauug  cu cu  gu c  a
      |||||||| ||||||  || ||  || |   
3'    cgggaaaa uguaac  ga ga  ca g  c
   cua        u      gu  c  gc  u ug 

Deep sequencing

267209 reads, 1.35e+03 reads per million, 106 experiments

Confidence

Annotation confidence: high

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Comments

This sequence was named miR-130 in reference [1], but is renamed here to avoid confusion with miR-130b (MI0000408).

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr2: 84741115-84741178 [-]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:Mir130a
• MGI:Mir130a
• RNAcentral:URS000075D38A_10090
• miRBase Tracker:MI0000156

Mature sequence mmu-miR-130a-5p

• Accession: MIMAT0016983
• Previous IDs: mmu-miR-130a*
• Sequence: 3 - gcucuuuucacauugugcuacu - 24
• Deep sequencing: 491 reads, 54 experiments
• Evidence: experimental; Illumina [8]
• Database links:
  • RNAcentral:URS0000229ECD_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-130a-5p
  • miRDB:mmu-miR-130a-5p

Mature sequence mmu-miR-130a-3p

• Accession: MIMAT0000141
• Previous IDs: mmu-miR-130a
• Sequence: 42 - cagugcaauguuaaaagggcau - 63
• Deep sequencing: 266698 reads, 106 experiments
• Evidence: experimental; cloned [1-2,4-6], Northern [2], Illumina [7]
• Database links:
  • RNAcentral:URS0000315338_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-130a-3p
  • miRDB:mmu-miR-130a-3p
  • microrna.org:mmu-miR-130a-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
3. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
4. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
5. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
6. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
7. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
8. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).